Alitalo, Kari

Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor

Zheng, W., Tammela, T., Yamamoto, M., Anisimov, A., Holopainen, T., Kaijalainen, S., Karpanen, T., Lehti, K., Ylä-Herttuala, S., & Alitalo, K. (2011) · Blood

Lymphatic System and DiseasesAngiogenesis and VEGF in Cancer

Cited by 132

Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization

Leppänen, V.-M., Saharinen, P., & Alitalo, K. (2017) · Proceedings of the National Academy of Sciences

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 127

Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 – implications for microvascular inflammation and hypercoagulopathy in COVID-19

He, L., Mäe, M. A., Muhl, L., Sun, Y., Pietilä, R., Nahar, K., Liébanas, E. V., Fagerlund, M. J., Oldner, A., Liu, J., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 116

Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression

Korhonen, E. A., Murtomäki, A., Jha, S. K., Anisimov, A., Pink, A., Zhang, Y., Stritt, S., Liaqat, I., Stanczuk, L., Alderfer, L., et al. (2022) · Journal of Clinical Investigation

Lymphatic System and DiseasesAngiogenesis and VEGF in Cancer

Cited by 113

The cellular response to induction of the p21 c‐Ha‐ras oncoprotein includes stimulation of jun gene expression.

Sistonen, L., Hölttä, E., Mäkelä, T. P., Keski‐Oja, J., & Alitalo, K. (1989) · The EMBO Journal

Protein Kinase Regulation and GTPase SignalingPolyamine Metabolism and Applications

Cited by 109

Transcriptomal comparison of human dermal lymphatic endothelial cells ex vivo and in vitro

Wick, N., Saharinen, P., Saharinen, J., Gurnhofer, E., Steiner, C. W., Raab, I., Stokic, D., Giovanoli, P., Buchsbaum, S., Burchard, A., et al. (2007) · Physiological Genomics

Lymphatic System and DiseasesLymphatic Disorders and Treatments

Cited by 106

Transgenic Induction of Vascular Endothelial Growth Factor-C Is Strongly Angiogenic in Mouse Embryos but Leads to Persistent Lymphatic Hyperplasia in Adult Tissues

Lohela, M., Heloterä, H., Haiko, P., Dumont, D. J., & Alitalo, K. (2008) · The American Journal of Pathology

Lymphatic System and DiseasesLymphatic Disorders and Treatments

Cited by 73

Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS

Li, Z., Korhonen, E. A., Merlini, A., Strauss, J., Wihuri, E., Nurmi, H., Antila, S., Paech, J., Deutsch, U., Engelhardt, B., et al. (2020) · Journal of Clinical Investigation

Multiple Sclerosis Research StudiesBarrier Structure and Function Studies

Cited by 52

Characterization of ANGPT2 mutations associated with primary lymphedema

Leppänen, V.-M., Brouillard, P., Korhonen, E. A., Sipilä, T., Jha, S. K., Revencu, N., Labarque, V., Fastré, E., Schlögel, M., Ravoet, M., et al. (2020) · Science Translational Medicine

Lymphatic System and DiseasesLymphatic Disorders and Treatments

Cited by 49