Shannon, Kevin

Hyperactive Ras in developmental disorders and cancer

Schubbert, S., Shannon, K., & Bollag, G. (2007) · Nature Reviews Cancer

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 1,583

Germline KRAS mutations cause Noonan syndrome

Schubbert, S., Zenker, M., Rowe, S. L., Böll, S., Klein, C., Bollag, G., van der Burgt, I., Musante, L., Kalscheuer, V., Wehner, L.-E., et al. (2006) · Nature Genetics

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 730

The rate of telomere sequence loss in human leukocytes varies with age

Frenck, R. W., Blackburn, E. H., & Shannon, K. M. (1998) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 675

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

Haigis, K. M., Kendall, K. R., Wang, Y., Cheung, A., Haigis, M. C., Glickman, J. N., Niwa-Kawakita, M., Sweet-Cordero, A., Sebolt-Leopold, J., Shannon, K. M., et al. (2008) · Nature Genetics

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 610

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

Braun, B. S., Tuveson, D. A., Kong, N., Le, D. T., Kogan, S. C., Rozmus, J., Le Beau, M. M., Jacks, T. E., & Shannon, K. M. (2004) · Proceedings of the National Academy of Sciences

Acute Myeloid Leukemia ResearchProtein Tyrosine Phosphatases

Cited by 299

KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer

Burgess, M. R., Hwang, E., Mroue, R., Bielski, C. M., Wandler, A. M., Huang, B. J., Firestone, A. J., Young, A., Lacap, J. A., Crocker, L., et al. (2017) · Cell

Melanoma and MAPK PathwaysCancer Genomics and Diagnostics

Cited by 183

Nf1 Regulates Hematopoietic Progenitor Cell Growth and Ras Signaling in Response to Multiple Cytokines

Zhang, Y.-Y., Vik, T. A., Ryder, J. W., Srour, E. F., Jacks, T., Shannon, K., & Wade Clapp, D. (1998) · The Journal of Experimental Medicine

Neurofibromatosis and Schwannoma CasesProtein Tyrosine Phosphatases

Cited by 150

Inherited predispositions and hyperactive Ras in myeloid leukemogenesis

Lauchle, J. O., Braun, B. S., Loh, M. L., & Shannon, K. (2006) · Pediatric Blood & Cancer

Protein Tyrosine PhosphatasesAcute Myeloid Leukemia Research

Cited by 94

Targeting Ras in myeloid leukemias

Braun, B. S., & Shannon, K. (2008) · Clinical Cancer Research

Acute Myeloid Leukemia ResearchProtein Kinase Regulation and GTPase Signaling

Cited by 74

De novo design of Ras isoform selective binders

Zhang, J. Z., Li, X., Batingana, A. R., Liu, C., Jiang, H., Shannon, K., Huang, B. J., Wu, K., & Baker, D. (2026) · Cell Chemical Biology

Protein Kinase Regulation and GTPase SignalingComputational Drug Discovery Methods

Cited by 12