Ehrt, Sabine

Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages

Schnappinger, D., Ehrt, S., Voskuil, M. I., Liu, Y., Mangan, J. A., Monahan, I. M., Dolganov, G., Efron, B., Butcher, P. D., Nathan, C., et al. (2003) · The Journal of Experimental Medicine

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 1,420

Mycobacterial survival strategies in the phagosome: defence against host stresses

Ehrt, S., & Schnappinger, D. (2009) · Cellular Microbiology

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 448

A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis

Vandal, O. H., Pierini, L. M., Schnappinger, D., Nathan, C. F., & Ehrt, S. (2008) · Nature Medicine

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 368

Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis

Bosch, B., DeJesus, M. A., Poulton, N. C., Zhang, W., Engelhart, C. A., Zaveri, A., Lavalette, S., Ruecker, N., Trujillo, C., Wallach, J. B., et al. (2021) · Cell

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 316

Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

Nathan, C., Calingasan, N., Nezezon, J., Ding, A., Lucia, M. S., La Perle, K., Fuortes, M., Lin, M., Ehrt, S., Kwon, N. S., et al. (2005) · The Journal of Experimental Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 214

Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis

Lee, J. J., Lee, S.-K., Song, N., Nathan, T. O., Swarts, B. M., Eum, S.-Y., Ehrt, S., Cho, S.-N., & Eoh, H. (2019) · Nature Communications

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 122

Chemical Genetic Interaction Profiling Reveals Determinants of Intrinsic Antibiotic Resistance in Mycobacterium tuberculosis

Xu, W., DeJesus, M. A., Rücker, N., Engelhart, C. A., Wright, M. G., Healy, C., Lin, K., Wang, R., Park, S. W., Ioerger, T. R., et al. (2017) · Antimicrobial Agents and Chemotherapy

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 115

M. tuberculosis Induces Potent Activation of IDO-1, but This Is Not Essential for the Immunological Control of Infection

Blumenthal, A., Nagalingam, G., Huch, J. H., Walker, L., Guillemin, G. J., Smythe, G. A., Ehrt, S., Britton, W. J., & Saunders, B. M. (2012) · PLoS ONE

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 105

Inactivation of Fructose-1,6-Bisphosphate Aldolase Prevents Optimal Co-catabolism of Glycolytic and Gluconeogenic Carbon Substrates in Mycobacterium tuberculosis

Puckett, S., Trujillo, C., Eoh, H., Marrero, J., Spencer, J., Jackson, M., Schnappinger, D., Rhee, K., & Ehrt, S. (2014) · PLoS Pathogens

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 72

Mycobacterial EtfD contains an unusual linear [3Fe-4S] cluster and enables β-oxidation to drive proton pumping by the electron transport chain

Courbon, G. M., Makarov, V., Cole, S. T., Schnapinger, D., Ehrt, S., & Rubinstein, J. L. (2025) · The EMBO Journal

Enzyme Structure and FunctionTuberculosis Research and Epidemiology

Cited by 2

Structural basis for EtfD-mediated coupling of β-oxidation and the respiratory chain in mycobacteria

Courbon, G. M., Makarov, V., Cole, S. T., Schnapinger, D., Ehrt, S., & Rubinstein, J. L. (2026) · The EMBO Journal

Enzyme Structure and FunctionTuberculosis Research and Epidemiology

Cited by 1