Denny, William A.

Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions

Smaill, J. B., Rewcastle, G. W., Loo, J. A., Greis, K. D., Chan, O. H., Reyner, E. L., Lipka, E., Showalter, H. D. H., Vincent, P. W., Elliott, W. L., et al. (2000) · Journal of Medicinal Chemistry

Quinazolinone synthesis and applicationsHER2/EGFR in Cancer Research

Cited by 269

The role of hypoxia-activated prodrugs in cancer therapy

Denny, W. A. (2000) · The Lancet Oncology

Cancer, Hypoxia, and MetabolismBioactive Compounds and Antitumor Agents

Cited by 167

Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumors

Hicks, K. O., Siim, B. G., Jaiswal, J. K., Pruijn, F. B., Fraser, A. M., Patel, R., Hogg, A., Liyanage, H. D. S., Dorie, M. J., Brown, J. M., et al. (2010) · Clinical Cancer Research

Cancer, Hypoxia, and MetabolismBioactive Compounds and Antitumor Agents

Cited by 132

Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family

Smaill, J. B., Gonzales, A. J., Spicer, J. A., Lee, H., Reed, J. E., Sexton, K., Althaus, I. W., Zhu, T., Black, S. L., Blaser, A., et al. (2016) · Journal of Medicinal Chemistry

HER2/EGFR in Cancer ResearchQuinazolinone synthesis and applications

Cited by 63

Transcription Factors As Targets for DNA-Interacting Drugs

Gniazdowski, M., Denny, W., Nelson, S., & Czyz, M. (2003) · Current Medicinal Chemistry

DNA and Nucleic Acid ChemistryMetal complexes synthesis and properties

Cited by 52

Effects of anticancer drugs on transcription factor–DNA interactions

Gniazdowski, M., Denny, W. A., Nelson, S. M., & Czyz, M. (2005) · Expert Opinion on Therapeutic Targets

DNA and Nucleic Acid ChemistryMetal complexes synthesis and properties

Cited by 41