Snyder, Michael

Variation and genetic control of protein abundance in humans

Wu, L., Candille, S. I., Choi, Y., Xie, D., Jiang, L., Li-Pook-Than, J., Tang, H., & Snyder, M. (2013) · Nature

Genetic Associations and EpidemiologyAdvanced Proteomics Techniques and Applications

Cited by 364

Validation of biomarkers of aging

Moqri, M., Herzog, C., Poganik, J. R., Ying, K., Justice, J. N., Belsky, D. W., Higgins-Chen, A. T., Chen, B. H., Cohen, A. A., Fuellen, G., et al. (2024) · Nature Medicine

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 361

The human proteome project: current state and future direction

Legrain, P., Aebersold, R., Archakov, A., Bairoch, A., Bala, K., Beretta, L., Bergeron, J., Borchers, C. H., Corthals, G. L., Costello, C. E., et al. (2011) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 352

Extensive Variation in Chromatin States Across Humans

Kasowski, M., Kyriazopoulou-Panagiotopoulou, S., Grubert, F., Zaugg, J. B., Kundaje, A., Liu, Y., Boyle, A. P., Zhang, Q. C., Zakharia, F., Spacek, D. V., et al. (2013) · Science

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 339

An exercise-inducible metabolite that suppresses feeding and obesity

Li, V. L., He, Y., Contrepois, K., Liu, H., Kim, J. T., Wiggenhorn, A. L., Tanzo, J. T., Tung, A. S.-H., Lyu, X., Zushin, P.-J. H., et al. (2022) · Nature

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 331

Glucotypes reveal new patterns of glucose dysregulation

Hall, H., Perelman, D., Breschi, A., Limcaoco, P., Kellogg, R., McLaughlin, T., & Snyder, M. (2018) · PLOS Biology

Diabetes Management and ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 326

Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions

Grubert, F., Zaugg, J. B., Kasowski, M., Ursu, O., Spacek, D. V., Martin, A. R., Greenside, P., Srivas, R., Phanstiel, D. H., Pekowska, A., et al. (2015) · Cell

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 319

AlleleSeq: analysis of allele-specific expression and binding in a network framework.

Rozowsky, J., Abyzov, A., Wang, J., Alves, P., Raha, D., Harmanci, A., Leng, J., Bjornson, R., Kong, Y., Kitabayashi, N., et al. (2011) · Molecular Systems Biology

Genomics and Phylogenetic StudiesGenomics and Chromatin Dynamics

Cited by 316

A comprehensive map of mobile element insertion polymorphisms in humans

Stewart, C., Kural, D., Strömberg, M. P., Walker, J. A., Konkel, M. K., Stütz, A. M., Urban, A. E., Grubert, F., Lam, H. Y. K., Lee, W.-P., et al. (2011) · PLoS Genetics

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 307

mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice

Zhao, C., Yasumura, D., Li, X., Matthes, M., Lloyd, M., Nielsen, G., Ahern, K., Snyder, M., Bok, D., Dunaief, J. L., et al. (2011) · Journal of Clinical Investigation

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 303

Static and Dynamic DNA Loops form AP-1-Bound Activation Hubs during Macrophage Development

Phanstiel, D. H., Van Bortle, K., Spacek, D., Hess, G. T., Shamim, M. S., Machol, I., Love, M. I., Aiden, E. L., Bassik, M. C., & Snyder, M. P. (2017) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 299

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis

Ang, Y.-S., Rivas, R. N., Ribeiro, A. J. S., Srivas, R., Rivera, J., Stone, N. R., Pratt, K., Mohamed, T. M. A., Fu, J.-D., Spencer, C. I., et al. (2016) · Cell

Congenital heart defects researchGenomics and Chromatin Dynamics

Cited by 294

Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation

Rubin, A. J., Barajas, B. C., Furlan-Magaril, M., Lopez-Pajares, V., Mumbach, M. R., Howard, I., Kim, D. S., Boxer, L. D., Cairns, J., Spivakov, M., et al. (2017) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 293

The chromosome-centric human proteome project for cataloging proteins encoded in the genome

Paik, Y.-K., Jeong, S.-K., Omenn, G. S., Uhlen, M., Hanash, S., Cho, S. Y., Lee, H.-J., Na, K., Choi, E.-Y., Yan, F., et al. (2012) · Nature Biotechnology

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 288

Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing

Mahmoudi, S., Mancini, E., Xu, L., Moore, A., Jahanbani, F., Hebestreit, K., Srinivasan, R., Li, X., Devarajan, K., Prélot, L., et al. (2019) · Nature

Wound Healing and TreatmentsPluripotent Stem Cells Research

Cited by 285

Genome-wide map of regulatory interactions in the human genome

Heidari, N., Phanstiel, D. H., He, C., Grubert, F., Jahanbani, F., Kasowski, M., Zhang, M. Q., & Snyder, M. P. (2014) · Genome Research

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 278

Defining a personal, allele-specific, and single-molecule long-read transcriptome

Tilgner, H., Grubert, F., Sharon, D., & Snyder, M. P. (2014) · Proceedings of the National Academy of Sciences

Genomics and Phylogenetic StudiesRNA Research and Splicing

Cited by 266

Wearable sensors enable personalized predictions of clinical laboratory measurements

Dunn, J., Kidzinski, L., Runge, R., Witt, D., Hicks, J. L., Schüssler-Fiorenza Rose, S. M., Li, X., Bahmani, A., Delp, S. L., Hastie, T., et al. (2021) · Nature Medicine

Non-Invasive Vital Sign MonitoringArtificial Intelligence in Healthcare

Cited by 244

Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes

Sberro, H., Fremin, B. J., Zlitni, S., Edfors, F., Greenfield, N., Snyder, M. P., Pavlopoulos, G. A., Kyrpides, N. C., & Bhatt, A. S. (2019) · Cell

Genomics and Phylogenetic StudiesGut microbiota and health

Cited by 237

Extensive In Vivo Metabolite-Protein Interactions Revealed by Large-Scale Systematic Analyses

Li, X., Gianoulis, T. A., Yip, K. Y., Gerstein, M., & Snyder, M. (2010) · Cell

Fungal and yeast genetics researchAdvanced Proteomics Techniques and Applications

Cited by 237

Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events

Tilgner, H., Jahanbani, F., Blauwkamp, T., Moshrefi, A., Jaeger, E., Chen, F., Harel, I., Bustamante, C. D., Rasmussen, M., & Snyder, M. P. (2015) · Nature Biotechnology

RNA Research and SplicingGenomics and Phylogenetic Studies

Cited by 223

Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy

Lee, J., Termglinchan, V., Diecke, S., Itzhaki, I., Lam, C. K., Garg, P., Lau, E., Greenhaw, M., Seeger, T., Wu, H., et al. (2019) · Nature

Cardiomyopathy and Myosin StudiesCardiac electrophysiology and arrhythmias

Cited by 222

Dynamic Human Environmental Exposome Revealed by Longitudinal Personal Monitoring

Jiang, C., Wang, X., Li, X., Inlora, J., Wang, T., Liu, Q., & Snyder, M. (2018) · Cell

Health, Environment, Cognitive AgingIndoor Air Quality and Microbial Exposure

Cited by 218

A high-stringency blueprint of the human proteome

Adhikari, S., Nice, E. C., Deutsch, E. W., Lane, L., Omenn, G. S., Pennington, S. R., Paik, Y.-K., Overall, C. M., Corrales, F. J., Cristea, I. M., et al. (2020) · Nature Communications

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 210