Hughes, Adam L.

Regulation of Sterol Synthesis in Eukaryotes

Espenshade, P. J., & Hughes, A. L. (2007) · Annual Review of Genetics

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 593

An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast

Hughes, A. L., & Gottschling, D. E. (2012) · Nature

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 559

SREBP pathway responds to sterols and functions as an oxygen sensor in fission yeast.

Hughes, A. L., Todd, B. L., & Espenshade, P. J. (2005) · Cell

Cancer, Lipids, and MetabolismFungal and yeast genetics research

Cited by 320

Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.

Todd, B. L., Stewart, E. V., Burg, J. S., Hughes, A. L., & Espenshade, P. J. (2006) · Molecular and Cellular Biology

Fungal and yeast genetics researchCancer, Hypoxia, and Metabolism

Cited by 172

4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress.

Hughes, A. L., Lee, C.-Y. S., Bien, C. M., & Espenshade, P. J. (2007) · Journal of Biological Chemistry

Fungal and yeast genetics researchCancer, Lipids, and Metabolism

Cited by 60