Chiang, Cheng‐Ming

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

Shu, S., Lin, C. Y., He, H. H., Witwicki, R. M., Tabassum, D. P., Roberts, J. M., Janiszewska, M., Jin Huh, S., Liang, Y., Ryan, J., et al. (2016) · Nature

Protein Degradation and InhibitorsChromatin Remodeling and Cancer

Cited by 632

BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer

Li, X., Baek, G., Ramanand, S. G., Sharp, A., Gao, Y., Yuan, W., Welti, J., Rodrigues, D. N., Dolling, D., Figueiredo, I., et al. (2018) · Cell Reports

Protein Degradation and InhibitorsDNA Repair Mechanisms

Cited by 148

A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity

Kim, D., Xiao, Z., Kwon, S., Sun, X., Ryerson, D., Tkac, D., Ma, P., Wu, S., Chiang, C., Zhou, E., et al. (2015) · The EMBO Journal

Adipokines, Inflammation, and Metabolic DiseasesPeroxisome Proliferator-Activated Receptors

Cited by 126

Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding

Wu, S., & Chiang, C. (2009) · The EMBO Journal

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 125

EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer

Gong, K., Guo, G., Panchani, N., Bender, M. E., Gerber, D. E., Minna, J. D., Fattah, F., Gao, B., Peyton, M., Kernstine, K., et al. (2020) · Nature Cancer

Lung Cancer Treatments and Mutationsinterferon and immune responses

Cited by 92

Dual‐target inhibitors of bromodomain and extra‐terminal proteins in cancer: A review from medicinal chemistry perspectives

Feng, L., Wang, G., Chen, Y., He, G., Liu, B., Liu, J., Chiang, C., & Ouyang, L. (2022) · Medicinal Research Reviews

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

Cited by 65

Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver

Dubois, V., Gheeraert, C., Vankrunkelsven, W., Dubois‐Chevalier, J., Dehondt, H., Bobowski‐Gerard, M., Vinod, M., Zummo, F. P., Güiza, F., Ploton, M., et al. (2020) · Molecular Systems Biology

Liver physiology and pathologyEndoplasmic Reticulum Stress and Disease

Cited by 46