Aspnes, Gary

Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

Futatsugi, K., Kung, D. W., Orr, S. T. M., Cabral, S., Hepworth, D., Aspnes, G., Bader, S., Bian, J., Boehm, M., Carpino, P. A., et al. (2015) · Journal of Medicinal Chemistry

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 88

A potentiator of orthosteric ligand activity at GLP-1R acts via covalent modification

Nolte, W. M., Fortin, J.-P., Stevens, B. D., Aspnes, G. E., Griffith, D. A., Hoth, L. R., Ruggeri, R. B., Mathiowetz, A. M., Limberakis, C., Hepworth, D., et al. (2014) · Nature Chemical Biology

Receptor Mechanisms and SignalingDiabetes Treatment and Management

Cited by 86

Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells

Li, W., Sparks, R. P., Sun, C., Yang, Y., Pantano, L., Kirchner, R., Arghiani, N., Weilheimer, A., Toles, B. J., Chen, J. Y., et al. (2025) · Nature Communications

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 5

Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells

Li, W., Sparks, R. P., Sun, C., Yang, Y., Pantano, L., Kirchner, R., Weilheimer, A., Toles, B. J., Chen, J. Y., Moran, S. P., et al. (2023) · Nature Communications

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 5