Chapman, Matthew R.

A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice

Sampson, T. R., Challis, C., Jain, N., Moiseyenko, A., Ladinsky, M. S., Shastri, G. G., Thron, T., Needham, B. D., Horvath, I., Debelius, J. W., et al. (2020) · eLife

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 439

Diversity, biogenesis and function of microbial amyloids

Blanco, L. P., Evans, M. L., Smith, D. R., Badtke, M. P., & Chapman, M. R. (2012) · Trends in Microbiology

Biochemical and Structural CharacterizationAlzheimer's disease research and treatments

Cited by 320

Determining crystal structures through crowdsourcing and coursework

Horowitz, S., Koepnick, B., Martin, R., Tymieniecki, A., Winburn, A. A., Cooper, S., Flatten, J., Rogawski, D. S., Koropatkin, N. M., Hailu, T. T., et al. (2016) · Nature Communications

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 75

The bacterial chaperone CsgC inhibits functional amyloid CsgA formation by promoting the intrinsically disordered pre-nuclear state

Balistreri, A., Kolli, D., Jayaweera, S. W., Lundahl, D., Han, Y., Kalcec, L., Goetzler, E., Alessio, R., Ruotolo, B., Olofsson, A., et al. (2025) · Journal of Biological Chemistry

Heat shock proteins researchAlzheimer's disease research and treatments

Cited by 10

The bacterial chaperone CsgC inhibits functional amyloid CsgA formation by promoting the intrinsically disordered pre-nuclear state

Balistreri, A., Kolli, D., Jayaweera, S. W., Lundahl, D., Han, Y., Kalcec, L., Goetzler, E., Alessio, R., Ruotolo, B., Olofsson, A., et al. (2025) · Journal of Biological Chemistry

Heat shock proteins researchAlzheimer's disease research and treatments

Cited by 10