Segal, Anthony W.

Killing activity of neutrophils is mediated through activation of proteases by K+ flux

Reeves, E. P., Lu, H., Jacobs, H. L., Messina, C. G. M., Bolsover, S., Gabella, G., Potma, E. O., Warley, A., Roes, J., & Segal, A. W. (2002) · Nature

Neutrophil, Myeloperoxidase and Oxidative MechanismsAntimicrobial Peptides and Activities

Cited by 1,153

The NADPH oxidase of professional phagocytes—prototype of the NOX electron transport chain systems

Cross, A. R., & Segal, A. W. (2004) · Biochimica et Biophysica Acta (BBA) - Bioenergetics

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 489

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease

Hui, K. Y., Fernandez-Hernandez, H., Hu, J., Schaffner, A., Pankratz, N., Hsu, N.-Y., Chuang, L.-S., Carmi, S., Villaverde, N., Li, X., et al. (2018) · Science Translational Medicine

Parkinson's Disease Mechanisms and TreatmentsInflammatory Bowel Disease

Cited by 384

Absence of both cytochrome b−245 subunits from neutrophils in X-linked chronic granulomatous disease

Segal, A. W. (1987) · Nature

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 316

p40 phox , a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains

Wientjes, F. B., Hsuan, J. J., Totty, N. F., & Segal, A. W. (1993) · Biochemical Journal

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 301

Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein

Segal, A. W., Heyworth, P. G., Cockcroft, S., & Barrowman, M. M. (1985) · Nature

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 281

Intramembrane Bis-Heme Motif for Transmembrane Electron Transport Conserved in a Yeast Iron Reductase and the Human NADPH Oxidase

Finegold, A. A., Shatwell, K. P., Segal, A. W., Klausner, R. D., & Dancis, A. (1996) · Journal of Biological Chemistry

Metalloenzymes and iron-sulfur proteinsMetal-Catalyzed Oxygenation Mechanisms

Cited by 213

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

Rivas, M. A., Avila, B. E., Koskela, J., Huang, H., Stevens, C., Pirinen, M., Haritunians, T., Neale, B. M., Kurki, M., Ganna, A., et al. (2018) · PLoS Genetics

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 87

Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation

O’Shea, N. R., Chew, T. S., Dunne, J., Marnane, R., Nedjat-Shokouhi, B., Smith, P. J., Bloom, S. L., Smith, A. M., & Segal, A. W. (2016) · Journal of Crohn's and Colitis

Inflammatory Bowel DiseaseProtease and Inhibitor Mechanisms

Cited by 53