Koehler, Angela N.

Advances in Targeting ‘Undruggable’ transcription Factors With Small Molecules

Henley, M. J., & Koehler, A. N. (2021) · Nature Reviews Drug Discovery

Protein Degradation and InhibitorsComputational Drug Discovery Methods

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A complex task? Direct modulation of transcription factors with small molecules

Koehler, A. N. (2010) · Current Opinion in Chemical Biology

Protein Degradation and InhibitorsComputational Drug Discovery Methods

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Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription

Struntz, N. B., Chen, A., Deutzmann, A., Wilson, R. M., Stefan, E., Evans, H. L., Ramirez, M. A., Liang, T., Caballero, F., Wildschut, M. H. E., et al. (2019) · Cell Chemical Biology

Chemical Synthesis and AnalysisCancer-related Molecular Pathways

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Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics

de Waal, L., Lewis, T. A., Rees, M. G., Tsherniak, A., Wu, X., Choi, P. S., Gechijian, L., Hartigan, C., Faloon, P. W., Hickey, M. J., et al. (2016) · Nature Chemical Biology

Phosphodiesterase function and regulationComputational Drug Discovery Methods

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Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

Richters, A., Doyle, S. K., Freeman, D. B., Lee, C., Leifer, B. S., Jagannathan, S., Kabinger, F., Koren, J. V., Struntz, N. B., Urgiles, J., et al. (2021) · Cell Chemical Biology

Prostate Cancer Treatment and ResearchProtein Degradation and Inhibitors

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