Chavez, Alejandro

Age-related clonal hematopoiesis associated with adverse outcomes

Jaiswal, S., Fontanillas, P., Flannick, J., Manning, A., Grauman, P. V., Mar, B. G., Lindsley, R. C., Mermel, C. H., Burtt, N., Chavez, A., et al. (2014) · New England Journal of Medicine

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 4,841

Highly efficient Cas9-mediated transcriptional programming

Chavez, A., Scheiman, J., Vora, S., Pruitt, B. W., Tuttle, M., P R Iyer, E., Lin, S., Kiani, S., Guzman, C. D., Wiegand, D. J., et al. (2015) · Nature Methods

CRISPR and Genetic EngineeringPluripotent Stem Cells Research

Cited by 1,622

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

Rock, J. M., Hopkins, F. F., Chavez, A., Diallo, M., Chase, M. R., Gerrick, E. R., Pritchard, J. R., Church, G. M., Rubin, E. J., Sassetti, C. M., et al. (2017) · Nature Microbiology

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 538

Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

Nollen, E. A. A., Garcia, S. M., van Haaften, G., Kim, S., Chavez, A., Morimoto, R. I., & Plasterk, R. H. A. (2004) · Proceedings of the National Academy of Sciences

Genetic Neurodegenerative DiseasesAmyotrophic Lateral Sclerosis Research

Cited by 416

Accurate analysis of genuine CRISPR editing events with ampliCan

Labun, K., Guo, X., Chavez, A., Church, G., Gagnon, J. A., & Valen, E. (2019) · Genome Research

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 84

Rational design of a compact CRISPR-Cas9 activator for AAV-mediated delivery

Vora, S., Cheng, J., Xiao, R., VanDusen, N. J., Quintino, L., Pu, W. T., Vandenberghe, L. H., Chavez, A., & Church, G. (2018) · bioRxiv (Cold Spring Harbor Laboratory)

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 42

Enabling multiplexed testing of pooled donor cells through whole-genome sequencing

Chan, Y., Chan, Y. K., Goodman, D. B., Guo, X., Chavez, A., Lim, E. T., & Church, G. M. (2018) · Genome Medicine

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 17