Mead, Adam J.

Whole-genome sequencing of patients with rare diseases in a national health system

Turro, E., Astle, W. J., Megy, K., Gräf, S., Greene, D., Shamardina, O., Allen, H. L., Sanchis-Juan, A., Frontini, M., Thys, C., et al. (2020) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 554

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia

Giustacchini, A., Thongjuea, S., Barkas, N., Woll, P. S., Povinelli, B. J., Booth, C. A. G., Sopp, P., Norfo, R., Rodriguez-Meira, A., Ashley, N., et al. (2017) · Nature Medicine

Chronic Myeloid Leukemia TreatmentsSingle-cell and spatial transcriptomics

Cited by 403

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Ahern, D. J., Ai, Z., Ainsworth, M., Allan, C., Allcock, A., Angus, B., Ansari, M. A., Arancibia-Cárcamo, C. V., Aschenbrenner, D., Attar, M., et al. (2022) · Cell

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 328

Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing

Rodriguez-Meira, A., Buck, G., Clark, S.-A., Povinelli, B. J., Alcolea, V., Louka, E., McGowan, S., Hamblin, A., Sousos, N., Barkas, N., et al. (2019) · Molecular Cell

Single-cell and spatial transcriptomicsCancer Genomics and Diagnostics

Cited by 305

Single-Cell Analyses Reveal Megakaryocyte-Biased Hematopoiesis in Myelofibrosis and Identify Mutant Clone-Specific Targets

Psaila, B., Wang, G., Rodriguez-Meira, A., Li, R., Heuston, E. F., Murphy, L., Yee, D., Hitchcock, I. S., Sousos, N., O’Sullivan, J., et al. (2020) · Molecular Cell

Myeloproliferative Neoplasms: Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 185

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution

Rodriguez-Meira, A., Norfo, R., Wen, S., Chédeville, A. L., Rahman, H., O’Sullivan, J., Wang, G., Louka, E., Kretzschmar, W. W., Paterson, A., et al. (2023) · Nature Genetics

Acute Myeloid Leukemia ResearchCancer Genomics and Diagnostics

Cited by 158

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential

Luc, S., Luis, T. C., Boukarabila, H., Macaulay, I. C., Buza-Vidas, N., Bouriez-Jones, T., Lutteropp, M., Woll, P. S., Loughran, S. J., Mead, A. J., et al. (2012) · Nature Immunology

T-cell and B-cell ImmunologyHematopoietic Stem Cell Transplantation

Cited by 152

From pioneer to repressor: Bimodal foxd3 activity dynamically remodels neural crest regulatory landscape in vivo

Gavriouchkina, D., Williams, R. M., Lukoseviciute, M., Hochgreb-Hägele, T., Senanayake, U., Chong-Morrison, V., Thongjuea, S., Repapi, E., Mead, A., & Sauka-Spengler, T. (2017) · Developmental Cell

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 116

From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo

Lukoseviciute, M., Gavriouchkina, D., Williams, R. M., Hochgreb-Hagele, T., Senanayake, U., Chong-Morrison, V., Thongjuea, S., Repapi, E., Mead, A., & Sauka-Spengler, T. (2018) · Developmental Cell

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 109

A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors

Buono, M., Facchini, R., Matsuoka, S., Thongjuea, S., Waithe, D., Luis, T. C., Giustacchini, A., Besmer, P., Mead, A. J., Jacobsen, S. E. W., et al. (2016) · Nature Cell Biology

T-cell and B-cell ImmunologyHematopoietic Stem Cell Transplantation

Cited by 79

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

Booth, C. A. G., Barkas, N., Neo, W. H., Boukarabila, H., Soilleux, E. J., Giotopoulos, G., Farnoud, N., Giustacchini, A., Ashley, N., Carrelha, J., et al. (2018) · Cancer Cell

Acute Myeloid Leukemia ResearchAcute Lymphoblastic Leukemia research

Cited by 57

De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures

Ito, Y., Carss, K. J., Duarte, S. T., Hartley, T., Keren, B., Kurian, M. A., Marey, I., Charles, P., Mendonça, C., Nava, C., et al. (2018) · The American Journal of Human Genetics

Genetics and Neurodevelopmental DisordersGenomics and Rare Diseases

Cited by 41