Grosveld, Gerard

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Zhou, S., Schuetz, J. D., Bunting, K. D., Colapietro, A.-M., Sampath, J., Morris, J. J., Lagutina, I., Grosveld, G. C., Osawa, M., Nakauchi, H., et al. (2001) · Nature Medicine

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

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Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

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Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19

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Cancer-related Molecular PathwaysTelomeres, Telomerase, and Senescence

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A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

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Chronic Myeloid Leukemia TreatmentsT-cell and Retrovirus Studies

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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

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An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

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Lymphatic System and DiseasesLymphatic Disorders and Treatments

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Characterization of human lysosomal neuraminidase defines the molecular basis of the metabolic storage disorder sialidosis.

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The t(12;21) Translocation Converts AML-1B from an Activator to a Repressor of Transcription

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Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6

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