Haschka, David

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Theurl, I., Hilgendorf, I., Nairz, M., Tymoszuk, P., Haschka, D., Asshoff, M., He, S., Gerhardt, L. M. S., Holderried, T. A. W., Seifert, M., et al. (2016) · Nature Medicine

Phagocytosis and Immune RegulationIron Metabolism and Disorders

Cited by 412

Iron at the interface of immunity and infection

Nairz, M., Haschka, D., Demetz, E., & Weiss, G. (2014) · Frontiers in Pharmacology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 325

Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease

Mayr, L., Grabherr, F., Schwärzler, J., Reitmeier, I., Sommer, F., Gehmacher, T., Niederreiter, L., He, G.-W., Ruder, B., Kunz, K. T. R., et al. (2020) · Nature Communications

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 292

Iron in immune cell function and host defense

Haschka, D., Hoffmann, A., & Weiss, G. (2021) · Seminars in Cell & Developmental Biology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 188

Persisting alterations of iron homeostasis in COVID-19 are associated with non-resolving lung pathologies and poor patients’ performance: a prospective observational cohort study

Sonnweber, T., Boehm, A., Sahanic, S., Pizzini, A., Aichner, M., Sonnweber, B., Kurz, K., Koppelstätter, S., Haschka, D., Petzer, V., et al. (2020) · Respiratory Research

COVID-19 Clinical Research StudiesIron Metabolism and Disorders

Cited by 177

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

Sonnweber, T., Nachbaur, D., Schroll, A., Nairz, M., Seifert, M., Demetz, E., Haschka, D., Mitterstiller, A.-M., Kleinsasser, A., Burtscher, M., et al. (2014) · Gut

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 145

Iron and innate antimicrobial immunity-depriving the pathogen, defending the host

Nairz, M., Dichtl, S., Schroll, A., Haschka, D., Tymoszuk, P., Theurl, I., & Weiss, G. (2018) · Journal of Trace Elements in Medicine and Biology

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 123

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

Nairz, M., Ferring-Appel, D., Casarrubea, D., Sonnweber, T., Viatte, L., Schroll, A., Haschka, D., Fang, F. C., Hentze, M. W., Weiss, G., et al. (2015) · Cell Host & Microbe

Iron Metabolism and DisordersBacterial Genetics and Biotechnology

Cited by 103

Dopamine promotes cellular iron accumulation and oxidative stress responses in macrophages

Dichtl, S., Haschka, D., Nairz, M., Seifert, M., Volani, C., Lutz, O., & Weiss, G. (2018) · Biochemical Pharmacology

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 76

Lipocalin‐2 ensures host defense against Salmonella Typhimurium by controlling macrophage iron homeostasis and immune response

Nairz, M., Schroll, A., Haschka, D., Dichtl, S., Sonnweber, T., Theurl, I., Theurl, M., Lindner, E., Demetz, E., Aßhoff, M., et al. (2015) · European Journal of Immunology

Immune Response and InflammationIron Metabolism and Disorders

Cited by 67

Heme oxygenase 1 controls early innate immune response of macrophages to Salmonella Typhimurium infection: Heme oxygenase 1 expression affects Salmonella infection

Mitterstiller, A.-M., Haschka, D., Dichtl, S., Nairz, M., Demetz, E., Talasz, H., Soares, M. P., Einwallner, E., Esterbauer, H., Fang, F. C., et al. (2016) · Cellular Microbiology

Heme Oxygenase-1 and Carbon MonoxideHemoglobin structure and function

Cited by 62

Dietary iron loading negatively affects liver mitochondrial function

Volani, C., Doerrier, C., Demetz, E., Haschka, D., Paglia, G., Lavdas, A. A., Gnaiger, E., & Weiss, G. (2017) · Metallomics

Iron Metabolism and DisordersMitochondrial Function and Pathology

Cited by 59

Dopamine Is a Siderophore-Like Iron Chelator That Promotes Salmonella enterica Serovar Typhimurium Virulence in Mice

Dichtl, S., Demetz, E., Haschka, D., Tymoszuk, P., Petzer, V., Nairz, M., Seifert, M., Hoffmann, A., Brigo, N., Würzner, R., et al. (2019) · mBio

Bacterial Genetics and BiotechnologySalmonella and Campylobacter epidemiology

Cited by 50

Genetic and Dietary Iron Overload Differentially Affect the Course of Salmonella Typhimurium Infection

Nairz, M., Schroll, A., Haschka, D., Dichtl, S., Tymoszuk, P., Demetz, E., Moser, P., Haas, H., Fang, F. C., Theurl, I., et al. (2017) · Frontiers in Cellular and Infection Microbiology

Iron Metabolism and DisordersSalmonella and Campylobacter epidemiology

Cited by 46

Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

Theurl, M., Nairz, M., Schroll, A., Sonnweber, T., Asshoff, M., Haschka, D., Seifert, M., Willenbacher, W., Wilflingseder, D., Posch, W., et al. (2014) · Haematologica

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 42

Impaired hepcidin expression in alpha-1-antitrypsin deficiency associated with iron overload and progressive liver disease

Schaefer, B., Haschka, D., Finkenstedt, A., Petersen, B.-S., Theurl, I., Henninger, B., Janecke, A. R., Wang, C.-Y., Lin, H. Y., Veits, L., et al. (2015) · Human Molecular Genetics

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 35

Classical and intermediate monocytes scavenge non-transferrin-bound iron and damaged erythrocytes

Haschka, D., Petzer, V., Kocher, F., Tschurtschenthaler, C., Schaefer, B., Seifert, M., Sopper, S., Sonnweber, T., Feistritzer, C., Arvedson, T. L., et al. (2019) · JCI Insight

Iron Metabolism and DisordersPhagocytosis and Immune Regulation

Cited by 34

Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria

Haschka, D., Nairz, M., Demetz, E., Wienerroither, S., Decker, T., & Weiss, G. (2015) · Metallomics

Iron Metabolism and DisordersImmune responses and vaccinations

Cited by 29