Bredemeyer, Andrea

Tissue Resident CCR2− and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury

Bajpai, G., Bredemeyer, A., Li, W., Zaitsev, K., Koenig, A. L., Lokshina, I., Mohan, J., Ivey, B., Hsiao, H.-M., Weinheimer, C., et al. (2019) · Circulation Research

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

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The human heart contains distinct macrophage subsets with divergent origins and functions

Bajpai, G., Schneider, C., Wong, N., Bredemeyer, A., Hulsmans, M., Nahrendorf, M., Epelman, S., Kreisel, D., Liu, Y., Itoh, A., et al. (2018) · Nature Medicine

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

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Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure

Koenig, A. L., Shchukina, I., Amrute, J., Andhey, P. S., Zaitsev, K., Lai, L., Bajpai, G., Bredemeyer, A., Smith, G., Jones, C., et al. (2022) · Nature Cardiovascular Research

Single-cell and spatial transcriptomicsCardiac Fibrosis and Remodeling

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Targeting immune–fibroblast cell communication in heart failure

Amrute, J. M., Luo, X., Penna, V., Yang, S., Yamawaki, T., Hayat, S., Bredemeyer, A., Jung, I.-H., Kadyrov, F. F., Heo, G. S., et al. (2024) · Nature

Cardiac Fibrosis and RemodelingCongenital heart defects research

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Formation of Dynamic γ-H2AX Domains along Broken DNA Strands Is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin

Savic, V., Yin, B., Maas, N. L., Bredemeyer, A. L., Carpenter, A. C., Helmink, B. A., Yang-Iott, K. S., Sleckman, B. P., & Bassing, C. H. (2009) · Molecular Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 204

SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis

Bailey, A. L., Dmytrenko, O., Greenberg, L., Bredemeyer, A. L., Ma, P., Liu, J., Penna, V., Winkler, E. S., Sviben, S., Brooks, E., et al. (2021) · JACC: Basic to Translational Science

Viral Infections and Immunology ResearchCOVID-19 Clinical Research Studies

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Expansion of Pathogenic Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis

Ma, P., Liu, J., Qin, J., Lai, L., Heo, G. S., Luehmann, H., Sultan, D., Bredemeyer, A., Bajapa, G., Feng, G., et al. (2024) · Circulation

Cancer Immunotherapy and BiomarkersViral Infections and Immunology Research

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A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability

O'Connell, B. C., Adamson, B., Lydeard, J. R., Sowa, M. E., Ciccia, A., Bredemeyer, A. L., Schlabach, M., Gygi, S. P., Elledge, S. J., & Harper, J. W. (2010) · Molecular Cell

DNA Repair MechanismsCancer therapeutics and mechanisms

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Defining cardiac functional recovery in end-stage heart failure at single-cell resolution

Amrute, J. M., Lai, L., Ma, P., Koenig, A. L., Kamimoto, K., Bredemeyer, A., Shankar, T. S., Kuppe, C., Kadyrov, F. F., Schulte, L. J., et al. (2023) · Nature Cardiovascular Research

Cardiac Fibrosis and RemodelingMechanical Circulatory Support Devices

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Targeting the Immune-Fibrosis Axis in Myocardial Infarction and Heart Failure

Amrute, J. M., Luo, X., Penna, V., Bredemeyer, A., Yamawaki, T., Heo, G. S., Shi, S., Koenig, A., Yang, S., Kadyrov, F., et al. (2022) · bioRxiv

Cardiac Fibrosis and RemodelingCongenital heart defects research

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Defining Cardiac Recovery at Single Cell Resolution

Amrute, J. M., Lai, L., Ma, P., Koenig, A. L., Kamimoto, K., Bredemeyer, A., Shankar, T. S., Kuppe, C., Kadyrov, F. F., Schulte, L. J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Cardiac Fibrosis and RemodelingCongenital heart defects research

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Hypoxia Sensing in Resident Cardiac Macrophages Regulates the Arg1 Macrophage Lineage During Ischemic Heart Injury

Kadyrov, F. F., Koenig, A. L., Amrute, J. M., Dun, H., Li, W., Weinheimer, C. J., Nigro, J. M., Kovacs, A., Bredemeyer, A. L., Lai, L., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Cardiac Fibrosis and RemodelingAtherosclerosis and Cardiovascular Diseases

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