Tejwani, Leon

Modeling of TREX1-dependent autoimmune disease using human stem cells highlights L1 accumulation as a source of neuroinflammation

Thomas, C. A., Tejwani, L., Trujillo, C. A., Negraes, P. D., Herai, R. H., Mesci, P., Macia, A., Crow, Y. J., & Muotri, A. R. (2017) · Cell Stem Cell

interferon and immune responsesSystemic Lupus Erythematosus Research

Cited by 330

Pharmacological reversal of synaptic and network pathology in human MECP2‐KO neurons and cortical organoids

Trujillo, C. A., Adams, J. W., Negraes, P. D., Carromeu, C., Tejwani, L., Acab, A., Tsuda, B., Thomas, C. A., Sodhi, N., Fichter, K. M., et al. (2021) · EMBO Molecular Medicine

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 101

Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43–related neurodegeneration

Tejwani, L., Jung, Y., Kokubu, H., Sowmithra, S., Ni, L., Lee, C., Sanders, B., Lee, P. J., Xiang, Y., Luttik, K., et al. (2023) · Journal of Clinical Investigation

Amyotrophic Lateral Sclerosis ResearchAutophagy in Disease and Therapy

Cited by 17

Microglia regulate brain progranulin levels through the endocytosis/lysosomal pathway

Dong, T., Tejwani, L., Jung, Y., Kokubu, H., Luttik, K., Driessen, T. M., & Lim, J. (2021) · JCI Insight

Neuroinflammation and Neurodegeneration MechanismsLysosomal Storage Disorders Research

Cited by 13

Lysosomes cell autonomously regulate myeloid cell states and immune responses

Tejwani, L., Balak, C., Skuja, L. L., Tatarakis, D., Rana, A., Fitzgerald, G. A., Ha, C., Lunkes de Melo, G., Sun, E. W., Heffner, C. M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

Neuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and Therapy

Cited by 4