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Paving Therapeutic Avenues for FOXG1 Syndrome: Untangling Genotypes and Phenotypes from a Molecular Perspective

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An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome

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Quantum Neurobiology

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KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs

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Modernising autism spectrum disorder model engineering and treatment via CRISPR-Cas9: A gene reprogramming approach

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Modeling antisense oligonucleotide therapy in MECP2 duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levels

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Alterations of presynaptic proteins in autism spectrum disorder

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Modeling Rett Syndrome with Human Pluripotent Stem Cells: Mechanistic Outcomes and Future Clinical Perspectives

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A Comprehensive Review on Utilizing Human Brain Organoids to Study Neuroinflammation in Neurological Disorders

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Analysis of the circRNA and T-UCR populations identifies convergent pathways in mouse and human models of Rett syndrome

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Music-Based Intervention Ameliorates Mecp2-Loss-Mediated Sociability Repression in Mice through the Prefrontal Cortex FNDC5/BDNF Pathway

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Brain Organoids to Evaluate Cellular Therapies

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High-content synaptic phenotyping in human cellular models reveals a role for BET proteins in synapse assembly

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Recent advances in stem cells and gene editing: Drug discovery and therapeutics

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Human Excitatory Cortical Neurospheroids Coupled to High-Density MEAs: A Valid Platform for Functional Tests

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Assessing the Utility of Organoid Intelligence: Scientific and Ethical Perspectives

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Human cerebral spheroids undergo 4-aminopyridine-induced, activity associated changes in cellular composition and microrna expression

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Neuromodulators generate multiple context-relevant behaviors in a recurrent neural network by shifting activity flows in hyperchannelsPreprint

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Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment

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NEAT1-mediated regulation of proteostasis and mRNA localization impacts autophagy dysregulation in Rett syndrome

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Impact of intermittent lead exposure on hominid brain evolution

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Microphysiological models of the central nervous system with fluid flow

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Integrating adult neurogenesis and human brain organoid models to advance epilepsy and associated behavioral research

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Neurodevelopmental disorders: 2022 update

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Three-dimensional human brain organoids: A next-generation model to decode Alzheimer’s disease

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MeCP2 regulates telencephalic development in human cerebral organoids

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Contraindicated Drug Responses in Dravet Syndrome Brain Organoids Utilizing Micro Electrode Array Assessment Methods

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Reconstructing human corticogenesis: Insights from cerebral organoids into neurodevelopment and disease modeling

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A Blueprint for Translational Precision Medicine in Autism Spectrum Disorder and Related Neurogenetic Syndromes

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Differentiation Defect Into GABAergic Neurons in Cerebral Organoids From Autism Patients

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Generation and Characterization of a Human Neuronal In Vitro Model for Rett Syndrome Using a Direct Reprogramming Method

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Aberrant Cortical Layer Development of Brain Organoids Derived from Noonan Syndrome-iPSCs

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Dormant viral pathways underlie space-induced neural senescencePreprint

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Proteomic dataset of MECP2-deficient and wild-type human brain organoids under spaceflight and ground conditions

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Therapeutic effects of CGS21680, a selective A2A receptor agonist, via BDNF-related pathways in R106W mutation Rett syndrome model

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Human pluripotent stem cell (hPSC)-derived models for autism spectrum disorder drug discovery

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Harnessing the potential of human induced pluripotent stem cells, functional assays and machine learning for neurodevelopmental disorders

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Modeling forebrain regional development and connectivity by human brain organoids

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Pluripotent stem cells-based neural organoids for modelling human brain development and diseases

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Zebrafish mecp2 null-mutation increases anxiety and cortisol levels but no change in adult social preference and larval chemically-induced hyperlocomotion

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How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle

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Human Brain Models of Intellectual Disability: Experimental Advances and Novelties

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Hypotheses of development and strategies for overcoming drug resistance in epilepsy. Рart II: Overcoming strategies

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Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutationsPreprint

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Large-area electrical imaging having single neuron resolution using 236,880 electrodes CMOS-MEA technologyPreprint

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CYFIP1 governs the development of cortical axons by modulating calcium availability

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Des organoïdes cérébraux pour la compréhension et la thérapie des maladies génétiques rares avec troubles neurodéveloppementaux

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Editorial: The 11th Edition of the International Meeting of the SPCE-TC: Advances in Stem Cells and Cell Therapies

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Label-free three-photon imaging of intact human cerebral organoids: tracking early events in brain development and deficits in Rett SyndromePreprint

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Probing the electrophysiological properties of patient-derived neurons across neurodevelopmental disorders

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Leveraging Microelectrode Array Technology for Phenotyping Stem Cell-Derived Neurodevelopmental Disease Models

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Additional file 3 of KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs

Xu, Y., Liu, P., Yan, Z.-Z., Mi, T., Wang, Y., Li, Q., Teng, Z., & Liu, C. (2023) · Figshare · doi:10.6084/m9.figshare.22605065

Human Cerebral Organoids in Pillar/Perfusion Plates for Modeling Neurodevelopmental Disorders

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Improvement of Behavioral Deficits in a Mouse Model of Fragile X Syndrome by Restoring α7 nAChR Hypofunction Associated with Aberrant Ly6H ExpressionPreprint

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When in vitro is not enough: In silico strategies to investigate functional and dynamical properties of large-scale neuronal assemblies

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Role of brain organoids in Rett syndrome

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Use of brain organoids for Parkinson's disease and Alzheimer's diseases

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Genetic Manipulation in Organoid Models and Their Applications in Central Nervous System Pathologies

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Mapping human neurodevelopment—Brain organoids meet lineage tracing

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Mecp2 deficiency impairs microscale cortical network topology and dynamics in a Rett syndrome mouse modelPreprint

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Additional file 2 of KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs

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Additional file 1 of KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs

Xu, Y.-J., Liu, P.-P., Yan, Z.-Z., 米廷伟, Wang, Y.-Y., Li, Q., 腾兆乾, & Liu, C.-M. (2023) · Figshare · doi:10.6084/m9.figshare.22605059

Advances in Stem Cell Research for MECP2-Related Disorders

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Brain repair and regeneration

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Human neuronal networks on micro-electrode arrays as a tool to assess genotype-phenotype correlation in CACNA1A-related disorders

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Neuromodulators Generate Multiple Context-Relevant Behaviors in Recurrent Neural Networks

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