Galbraith, Matthew D.

Trisomy 21 consistently activates the interferon response

Sullivan, K. D., Lewis, H. C., Hill, A. A., Pandey, A., Jackson, L. P., Cabral, J. M., Smith, K. P., Liggett, L. A., Gomez, E. B., Galbraith, M. D., et al. (2016) · eLife

Down syndrome and intellectual disability researchinterferon and immune responses

Cited by 362

Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome

Waugh, K. A., Araya, P., Pandey, A., Jordan, K. R., Smith, K. P., Granrath, R. E., Khanal, S., Butcher, E. T., Estrada, B. E., Rachubinski, A. L., et al. (2019) · Cell Reports

Down syndrome and intellectual disability researchinterferon and immune responses

Cited by 150

Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model

Waugh, K. A., Minter, R., Baxter, J., Chi, C., Galbraith, M. D., Tuttle, K. D., Eduthan, N. P., Kinning, K. T., Andrysik, Z., Araya, P., et al. (2023) · Nature Genetics

Down syndrome and intellectual disability researchinterferon and immune responses

Cited by 117

Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition

Galbraith, M. D., Rachubinski, A. L., Smith, K. P., Araya, P., Waugh, K. A., Enriquez-Estrada, B., Worek, K., Granrath, R. E., Kinning, K. T., Paul Eduthan, N., et al. (2023) · Science Advances

Down syndrome and intellectual disability researchinterferon and immune responses

Cited by 88

Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response

Andrysik, Z., Bender, H., Galbraith, M. D., & Espinosa, J. M. (2021) · Nature Communications

Cancer, Hypoxia, and MetabolismMechanisms of cancer metastasis

Cited by 63

IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome

Araya, P., Kinning, K. T., Coughlan, C., Smith, K. P., Granrath, R. E., Enriquez-Estrada, B. A., Worek, K., Sullivan, K. D., Rachubinski, A. L., Wolter-Warmerdam, K., et al. (2022) · Cell Reports

Down syndrome and intellectual disability researchGrowth Hormone and Insulin-like Growth Factors

Cited by 50

JAK inhibition decreases the autoimmune burden in Down syndrome

Rachubinski, A. L., Wallace, E., Gurnee, E., Enriquez-Estrada, B. A., Worek, K. R., Smith, K. P., Araya, P., Waugh, K. A., Granrath, R. E., Britton, E., et al. (2024) · eLife

Down syndrome and intellectual disability researchImmunodeficiency and Autoimmune Disorders

Cited by 32

Interferon signaling modulates Down syndrome-associated Alzheimer’s disease pathology in a mouse model

Araya, P., Niemeyer, B., Schade, K., Dunn, L. N., Waugh, K., Busquet, N., Brindley, C., Brown, C., Winkler, C., Lyford, H. R., et al. (2025) · iScience

Alzheimer's disease research and treatmentsDown syndrome and intellectual disability research

Cited by 7