Hooker, Jacob M.

Evidence for brain glial activation in chronic pain patients

Loggia, M. L., Chonde, D. B., Akeju, O., Arabasz, G., Catana, C., Edwards, R. R., Hill, E., Hsu, S., Izquierdo-Garcia, D., Ji, R.-R., et al. (2015) · Brain

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 503

Brain glial activation in fibromyalgia – A multi-site positron emission tomography investigation

Albrecht, D. S., Forsberg, A., Sandström, A., Bergan, C., Kadetoff, D., Protsenko, E., Lampa, J., Lee, Y. C., Höglund, C. O., Catana, C., et al. (2019) · Brain, Behavior, and Immunity

Fibromyalgia and Chronic Fatigue Syndrome ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 310

Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [11C]-PBR28

Zürcher, N. R., Loggia, M. L., Lawson, R., Chonde, D. B., Izquierdo-Garcia, D., Yasek, J. E., Akeju, O., Catana, C., Rosen, B. R., Cudkowicz, M. E., et al. (2015) · NeuroImage: Clinical

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 226

Dopamine in the medial amygdala network mediates human bonding

Atzil, S., Touroutoglou, A., Rudy, T., Salcedo, S., Feldman, R., Hooker, J. M., Dickerson, B. C., Catana, C., & Barrett, L. F. (2017) · Proceedings of the National Academy of Sciences

Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on Behavior

Cited by 182

Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness

Akeju, O., Loggia, M. L., Catana, C., Pavone, K. J., Vazquez, R., Rhee, J., Contreras Ramirez, V., Chonde, D. B., Izquierdo-Garcia, D., Arabasz, G., et al. (2014) · eLife

Functional Brain Connectivity StudiesAnesthesia and Sedative Agents

Cited by 168

A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests

Schroeder, F. A., Lewis, M. C., Fass, D. M., Wagner, F. F., Zhang, Y.-L., Hennig, K. M., Gale, J., Zhao, W.-N., Reis, S., Barker, D. D., et al. (2013) · PLoS ONE

Histone Deacetylase Inhibitors ResearchTreatment of Major Depression

Cited by 146

Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity

Porter, N. J., Osko, J. D., Diedrich, D., Kurz, T., Hooker, J. M., Hansen, F. K., & Christianson, D. W. (2018) · Journal of Medicinal Chemistry

Histone Deacetylase Inhibitors ResearchEnzyme function and inhibition

Cited by 111

Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET

Kim, S. W., Hooker, J. M., Otto, N., Win, K., Muench, L., Shea, C., Carter, P., King, P., Reid, A. E., Volkow, N. D., et al. (2013) · Nuclear Medicine and Biology

Histone Deacetylase Inhibitors ResearchRadiopharmaceutical Chemistry and Applications

Cited by 104

Toward an immune-mediated subtype of autism spectrum disorder

McDougle, C. J., Landino, S. M., Vahabzadeh, A., O’Rourke, J., Zurcher, N. R., Finger, B. C., Palumbo, M. L., Helt, J., Mullett, J. E., Hooker, J. M., et al. (2015) · Brain Research

Autism Spectrum Disorder ResearchTryptophan and brain disorders

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An Isochemogenic set of inhibitors to define the therapeutic potential of histone deacetylases in β-cell protection

Wagner, F. F., Lundh, M., Kaya, T., McCarren, P., Zhang, Y.-L., Chattopadhyay, S., Gale, J. P., Galbo, T., Fisher, S. L., Meier, B. C., et al. (2016) · ACS Chemical Biology

Histone Deacetylase Inhibitors ResearchEnzyme function and inhibition

Cited by 86

Neuroinflammation in Huntington’s Disease: New Insights with 11 C-PBR28 PET/MRI

Lois, C., González, I., Izquierdo-García, D., Zürcher, N. R., Wilkens, P., Loggia, M. L., Hooker, J. M., & Rosas, H. D. (2018) · ACS Chemical Neuroscience

Genetic Neurodegenerative DiseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 84

Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms

Manter, M. A., Birtwell, K. B., Bath, J., Friedman, N. D. B., Keary, C. J., Neumeyer, A. M., Palumbo, M. L., Thom, R. P., Stonestreet, E., Brooks, H., et al. (2025) · BMC Medicine

Autism Spectrum Disorder ResearchAttention Deficit Hyperactivity Disorder

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Visualizing epigenetics: Current advances and advantages in HDAC PET imaging techniques

Wang, C., Schroeder, F. A., & Hooker, J. M. (2014) · Neuroscience

Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation

Cited by 48

[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease

Pascoal, T. A., Chamoun, M., Lax, E., Wey, H.-Y., Shin, M., Ng, K. P., Kang, M. S., Mathotaarachchi, S., Benedet, A. L., Therriault, J., et al. (2022) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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