Casas, Juan P.

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

Abarca-Gómez, L., Abdeen, Z. A., Hamid, Z. A., Abu-Rmeileh, N. M., Acosta-Cazares, B., Acuin, C., Adams, R. J., Aekplakorn, W., Afsana, K., Aguilar-Salinas, C. A., et al. (2017) · The Lancet

Obesity, Physical Activity, DietCancer Risks and Factors

Cited by 7,482

Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis

Bellamy, L., Casas, J.-P., Hingorani, A. D., & Williams, D. (2009) · The Lancet

Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 3,253

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants

Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Danaei, G., Cowan, M. J., Paciorek, C. J., Singh, G., Hajifathalian, K., Bennett, J. E., et al. (2017) · The Lancet

Blood Pressure and Hypertension StudiesSodium Intake and Health

Cited by 2,579

Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis

Bellamy, L., Casas, J.-P., Hingorani, A. D., & Williams, D. J. (2007) · BMJ

Pregnancy and preeclampsia studiesNeurological Complications and Syndromes

Cited by 2,552

Mendelian randomization of blood lipids for coronary heart disease

Holmes, M. V., Asselbergs, F. W., Palmer, T. M., Drenos, F., Lanktree, M. B., Nelson, C. P., Dale, C. E., Padmanabhan, S., Finan, C., Swerdlow, D. I., et al. (2015) · European Heart Journal

Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health

Cited by 748

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

NCD Risk Factor Collaboration (NCD-RisC), Bixby, H., Bentham, J., Zhou, B., Di Cesare, M., Paciorek, C. J., Bennett, J. E., Taddei, C., Stevens, G. A., Rodriguez-Martinez, A., et al. (2019) · Nature

Obesity, Physical Activity, DietIndigenous Health and Education

Cited by 735

Plasma protein patterns as comprehensive indicators of health

Williams, S. A., Kivimaki, M., Langenberg, C., Hingorani, A. D., Casas, J. P., Bouchard, C., Jonasson, C., Sarzynski, M. A., Shipley, M. J., Alexander, L., et al. (2019) · Nature Medicine

Advanced Biosensing Techniques and ApplicationsHealth, Environment, Cognitive Aging

Cited by 506

CYP2C19 Genotype, Clopidogrel Metabolism, Platelet Function, and Cardiovascular Events: A Systematic Review and Meta-analysis

Holmes, M. V., Perel, P., Shah, T., Hingorani, A. D., & Casas, J. P. (2011) · JAMA

Antiplatelet Therapy and Cardiovascular DiseasesPharmacogenetics and Drug Metabolism

Cited by 472

Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program

Verma, A., Huffman, J. E., Rodriguez, A., Conery, M., Liu, M., Ho, Y.-L., Kim, Y., Heise, D. A., Guare, L., Panickan, V. A., et al. (2024) · Science

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 463

Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.

Swerdlow, D. I., Kuchenbaecker, K. B., Shah, S., Sofat, R., Holmes, M. V., White, J., Mindell, J. S., Kivimaki, M., Brunner, E. J., Whittaker, J. C., et al. (2016) · International Journal of Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 387

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Schmidt, A. F., Swerdlow, D. I., Holmes, M. V., Patel, R. S., Fairhurst-Hunter, Z., Lyall, D. M., Hartwig, F. P., Horta, B. L., Hyppönen, E., Power, C., et al. (2017) · The Lancet Diabetes & Endocrinology

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 380

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis

Dale, C. E., Fatemifar, G., Palmer, T. M., White, J., Prieto-Merino, D., Zabaneh, D., Engmann, J. E. L., Shah, T., Wong, A., Warren, H. R., et al. (2017) · Circulation

Genetic Associations and EpidemiologyCardiovascular Disease and Adiposity

Cited by 345

Preeclampsia and Cardiovascular Disease in a Large UK Pregnancy Cohort of Linked Electronic Health Records: A CALIBER Study

Leon, L. J., McCarthy, F. P., Direk, K., Gonzalez-Izquierdo, A., Prieto-Merino, D., Casas, J. P., & Chappell, L. (2019) · Circulation

Pregnancy and preeclampsia studiesNeurological Complications and Syndromes

Cited by 329

A chronological map of 308 physical and mental health conditions from 4 million individuals in the English National Health Service

Kuan, V., Denaxas, S., Gonzalez-Izquierdo, A., Direk, K., Bhatti, O., Husain, S., Sutaria, S., Hingorani, M., Nitsch, D., Parisinos, C. A., et al. (2019) · The Lancet Digital Health

Chronic Disease Management StrategiesMedical Coding and Health Information

Cited by 305

A road map for efficient and reliable human genome epidemiology.

The Human Genome Epidemiology Network and the Network of Investigator Networks, Ioannidis, J. P. A., Gwinn, M., Little, J., Higgins, J. P. T., Bernstein, J. L., Boffetta, P., Bondy, M., Bray, M. S., Brenchley, P. E., et al. (2006) · Nature Genetics

Genetic Associations and EpidemiologyMeta-analysis and systematic reviews

Cited by 244

Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis

Holmes, M. V., Lange, L. A., Palmer, T., Lanktree, M. B., North, K. E., Almoguera, B., Buxbaum, S., Chandrupatla, H. R., Elbers, C. C., Guo, Y., et al. (2014) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 216

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase

Würtz, P., Wang, Q., Soininen, P., Kangas, A. J., Fatemifar, G., Tynkkynen, T., Tiainen, M., Perola, M., Tillin, T., Hughes, A. D., et al. (2016) · Journal of the American College of Cardiology

Lipoproteins and Cardiovascular HealthMetabolomics and Mass Spectrometry Studies

Cited by 188

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Gabrielsen, M. E., Skorpen, F., Marioni, R. E., Campbell, A., Engmann, J., Mirza, S. S., Loukola, A., et al. (2014) · BMJ Open

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 187

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.

White, J., Sofat, R., Hemani, G., Shah, T., Engmann, J., Dale, C., Shah, S., Kruger, F. A., Giambartolomei, C., Swerdlow, D. I., et al. (2016) · The Lancet Diabetes & Endocrinology

Gout, Hyperuricemia, Uric AcidGenetic Associations and Epidemiology

Cited by 132

Separating the Mechanism-Based and Off-Target Actions of Cholesteryl Ester Transfer Protein Inhibitors With CETP Gene Polymorphisms

Sofat, R., Hingorani, A. D., Smeeth, L., Humphries, S. E., Talmud, P. J., Cooper, J., Shah, T., Sandhu, M. S., Ricketts, S. L., Boekholdt, S. M., et al. (2010) · Circulation

Lipoproteins and Cardiovascular HealthParaoxonase enzyme and polymorphisms

Cited by 104

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits

Silverwood, R. J., Holmes, M. V., Dale, C. E., Lawlor, D. A., Whittaker, J. C., Smith, G. D., Leon, D. A., Palmer, T., Keating, B. J., Zuccolo, L., et al. (2014) · International Journal of Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 66

Circulating apolipoprotein E concentration and cardiovascular disease risk: meta-analysis of results from three studies

Sofat, R., Cooper, J. A., Kumari, M., Casas, J. P., Mitchell, J. P., Acharya, J., Thom, S., Hughes, A. D., Humphries, S. E., & Hingorani, A. D. (2016) · PLOS Medicine

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 42

Alcohol consumption and cognitive performance: a Mendelian randomization study

Kumari, M., Holmes, M. V., Dale, C. E., Hubacek, J. A., Palmer, T. M., Pikhart, H., Peasey, A., Britton, A., Horvat, P., Kubinova, R., et al. (2014) · Addiction

Alcohol Consumption and Health EffectsGenetic Associations and Epidemiology

Cited by 31

PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort

Small, A. M., Huffman, J. E., Klarin, D., Lynch, J. A., Assimes, T., DuVall, S., Sun, Y. V., Shere, L., Natarajan, P., Gaziano, M., et al. (2020) · PLOS ONE

Lipoproteins and Cardiovascular HealthGenetic Associations and Epidemiology

Cited by 19