Kerk, Samuel A.

HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron

Singhal, R., Mitta, S. R., Das, N. K., Kerk, S. A., Sajjakulnukit, P., Solanki, S., Andren, A., Kumar, R., Olive, K. P., Banerjee, R., et al. (2021) · Journal of Clinical Investigation

Ferroptosis and cancer prognosisCancer, Hypoxia, and Metabolism

Cited by 215

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context

Kerk, S. A., Lin, L., Myers, A. L., Sutton, D. J., Andren, A., Sajjakulnukit, P., Zhang, L., Zhang, Y., Jiménez, J. A., Nelson, B. S., et al. (2022) · eLife

Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 108

Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming

Velez-Delgado, A., Donahue, K. L., Brown, K. L., Du, W., Irizarry-Negron, V., Menjivar, R. E., Lasse Opsahl, E. L., Steele, N. G., The, S., Lazarus, J., et al. (2022) · Cellular and Molecular Gastroenterology and Hepatology

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 91

High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions

Little, A. C., Kovalenko, I., Goo, L. E., Hong, H. S., Kerk, S. A., Yates, J. A., Purohit, V., Lombard, D. B., Merajver, S. D., & Lyssiotis, C. A. (2020) · Communications Biology

Mitochondrial Function and PathologyCancer, Hypoxia, and Metabolism

Cited by 88

Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells

Halbrook, C. J., Thurston, G., Boyer, S., Anaraki, C., Jiménez, J. A., McCarthy, A., Steele, N. G., Kerk, S. A., Hong, H. S., Lin, L., et al. (2022) · Nature Cancer

Cancer, Hypoxia, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 80

Therapeutic inhibition of the MDM2-p53 interaction prevents recurrence of adenoid cystic carcinomas

Nör, F., Warner, K. A., Zhang, Z., Acasigua, G. A., Pearson, A. T., Kerk, S. A., Helman, J. I., Sant'Ana Filho, M., Wang, S., & Nör, J. E. (2017) · Clinical Cancer Research

Cancer-related Molecular PathwaysSalivary Gland Tumors Diagnosis and Treatment

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