Ambs, Stefan

A microRNA expression signature of human solid tumors defines cancer gene targets

Volinia, S., Calin, G. A., Liu, C.-G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M., et al. (2006) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 5,697

The chemical biology of nitric oxide: Implications in cellular signaling

Thomas, D. D., Ridnour, L. A., Isenberg, J. S., Flores-Santana, W., Switzer, C. H., Donzelli, S., Hussain, P., Vecoli, C., Paolocci, N., Ambs, S., et al. (2008) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 975

MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis

Terunuma, A., Putluri, N., Mishra, P., Mathé, E. A., Dorsey, T. H., Yi, M., Wallace, T. A., Issaq, H. J., Zhou, M., Killian, J. K., et al. (2014) · Journal of Clinical Investigation

Cancer, Hypoxia, and MetabolismEpigenetics and DNA Methylation

Cited by 428

Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients

Glynn, S. A., Boersma, B. J., Dorsey, T. H., Yi, M., Yfantis, H. G., Ridnour, L. A., Martin, D. N., Switzer, C. H., Hudson, R. S., Wink, D. A., et al. (2010) · Journal of Clinical Investigation

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 254

Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression

Ambs, S., Hussain, S. P., & Harris, C. C. (1997) · The FASEB Journal

Cancer-related Molecular PathwaysNitric Oxide and Endothelin Effects

Cited by 233

Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression

Heinecke, J. L., Ridnour, L. A., Cheng, R. Y. S., Switzer, C. H., Lizardo, M. M., Khanna, C., Glynn, S. A., Hussain, S. P., Young, H. A., Ambs, S., et al. (2014) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsImmune cells in cancer

Cited by 177

Relationship between p53 mutations and inducible nitric oxide synthase expression in human colorectal cancer

Ambs, S., Bennett, W. P., Merriam, W. G., Ogunfusika, M. O., Oser, S. M., Harrington, A. M., Shields, P. G., Felley-Bosco, E., Hussain, S. P., & Harris, C. C. (1999) · JNCI Journal of the National Cancer Institute

Nitric Oxide and Endothelin EffectsCancer-related Molecular Pathways

Cited by 166

Integrated proteotranscriptomics of breast cancer reveals globally increased protein-mRNA concordance associated with subtypes and survival

Tang, W., Zhou, M., Dorsey, T. H., Prieto, D. A., Wang, X. W., Ruppin, E., Veenstra, T. D., & Ambs, S. (2018) · Genome Medicine

Breast Cancer Treatment StudiesAdvanced Proteomics Techniques and Applications

Cited by 162

S-nitrosylation of EGFR and Src activates an oncogenic signaling network in human basal-like breast cancer

Switzer, C. H., Glynn, S. A., Cheng, R. Y.-S., Ridnour, L. A., Green, J. E., Ambs, S., & Wink, D. A. (2012) · Molecular Cancer Research

HER2/EGFR in Cancer ResearchNitric Oxide and Endothelin Effects

Cited by 141

Superoxide fluxes limit nitric oxide-induced signaling

Thomas, D. D., Ridnour, L. A., Espey, M. G., Donzelli, S., Ambs, S., Hussain, S. P., Harris, C. C., DeGraff, W., Roberts, D. D., Mitchell, J. B., et al. (2006) · Journal of Biological Chemistry

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 121

Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer

Switzer, C. H., Cheng, R. Y.-S., Ridnour, L. A., Glynn, S. A., Ambs, S., & Wink, D. A. (2012) · Breast Cancer Research

Breast Cancer Treatment StudiesEstrogen and related hormone effects

Cited by 91

Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer

Switzer, C. H., Glynn, S. A., Ridnour, L. A., Cheng, R. Y.-S., Vitek, M. P., Ambs, S., & Wink, D. A. (2011) · Trends in Pharmacological Sciences

Breast Cancer Treatment StudiesNitric Oxide and Endothelin Effects

Cited by 74

Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation

Ridnour, L. A., Barasch, K. M., Windhausen, A. N., Dorsey, T. H., Lizardo, M. M., Yfantis, H. G., Lee, D. H., Switzer, C. H., Cheng, R. Y. S., Heinecke, J. L., et al. (2012) · PLoS ONE

Protease and Inhibitor MechanismsPI3K/AKT/mTOR signaling in cancer

Cited by 71

A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer

Auslander, N., Yizhak, K., Weinstock, A., Budhu, A., Tang, W., Wang, X. W., Ambs, S., & Ruppin, E. (2016) · Scientific Reports

Cancer, Hypoxia, and MetabolismMetabolomics and Mass Spectrometry Studies

Cited by 50

ADHFE1 is a MYC-linked oncogene that induces metabolic reprogramming and cellular de-differentiation in breast cancer

Mishra, P., Tang, W., & Ambs, S. (2018) · Molecular & Cellular Oncology

Cancer, Hypoxia, and MetabolismCancer, Lipids, and Metabolism

Cited by 16