Beech, David J.

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

Rode, B., Shi, J., Endesh, N., Drinkhill, M. J., Webster, P. J., Lotteau, S. J., Bailey, M. A., Yuldasheva, N. Y., Ludlow, M. J., Cubbon, R. M., et al. (2017) · Nature Communications

Ion Channels and ReceptorsErythrocyte Function and Pathophysiology

Cited by 305

Force Sensing by Piezo Channels in Cardiovascular Health and Disease

Beech, D. J., & Kalli, A. C. (2019) · Arteriosclerosis, Thrombosis, and Vascular Biology

Erythrocyte Function and PathophysiologyIon Channels and Receptors

Cited by 242

Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells

Caolo, V., Debant, M., Endesh, N., Futers, T. S., Lichtenstein, L., Bartoli, F., Parsonage, G., Jones, E. A., & Beech, D. J. (2020) · eLife

Developmental Biology and Gene RegulationCellular Mechanics and Interactions

Cited by 93

Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress

Endesh, N., Chuntharpursat‐Bon, E., Revill, C., Yuldasheva, N. Y., Futers, T. S., Parsonage, G., Humphreys, N., Adamson, A., Morley, L. C., Cubbon, R. M., et al. (2023) · Liver International

Ion Channels and ReceptorsCalcium signaling and nucleotide metabolism

Cited by 44

Selective Enhancement of Insulin Sensitivity in the Endothelium In Vivo Reveals a Novel Proatherosclerotic Signaling Loop

Viswambharan, H., Yuldasheva, N. Y., Sengupta, A., Imrie, H., Gage, M. C., Haywood, N., Walker, A. M. N., Skromna, A., Makova, N., Galloway, S., et al. (2017) · Circulation Research

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 43

Endothelial force sensing signals to parenchymal cells to regulate bile and plasma lipids

Lichtenstein, L., Cheng, C. W., Bajarwan, M., Evans, E. L., Gaunt, H. J., Bartoli, F., Chuntharpursat-Bon, E., Patel, S., Konstantinou, C., Futers, T. S., et al. (2024) · Science Advances

Cholesterol and Lipid MetabolismLiver physiology and pathology

Cited by 15