Owen, Bryn M.

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

Bookout, A. L., de Groot, M. H. M., Owen, B. M., Lee, S., Gautron, L., Lawrence, H. L., Ding, X., Elmquist, J. K., Takahashi, J. S., Mangelsdorf, D. J., et al. (2013) · Nature Medicine

Fibroblast Growth Factor ResearchCircadian rhythm and melatonin

Cited by 545

FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss

Owen, B. M., Ding, X., Morgan, D. A., Coate, K. C., Bookout, A. L., Rahmouni, K., Kliewer, S. A., & Mangelsdorf, D. J. (2014) · Cell Metabolism

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 523

A long-acting FGF21 molecule, PF-05231023, decreases body weight and improves lipid profile in non-human primates and type 2 diabetic subjects

Talukdar, S., Zhou, Y., Li, D., Rossulek, M., Dong, J., Somayaji, V., Weng, Y., Clark, R., Lanba, A., Owen, B. M., et al. (2016) · Cell Metabolism

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 496

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

Ding, X., Boney-Montoya, J., Owen, B. M., Bookout, A. L., Coate, K. C., Mangelsdorf, D. J., & Kliewer, S. A. (2012) · Cell Metabolism

Fibroblast Growth Factor ResearchParathyroid Disorders and Treatments

Cited by 403

FGF21 Regulates Sweet and Alcohol Preference

Talukdar, S., Owen, B. M., Song, P., Hernandez, G., Zhang, Y., Zhou, Y., Scott, W. T., Paratala, B., Turner, T., Smith, A., et al. (2016) · Cell Metabolism

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 342

Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21

Owen, B. M., Mangelsdorf, D. J., & Kliewer, S. A. (2015) · Trends in Endocrinology & Metabolism

Fibroblast Growth Factor ResearchParathyroid Disorders and Treatments

Cited by 286

FGF21 contributes to neuroendocrine control of female reproduction

Owen, B. M., Bookout, A. L., Ding, X., Lin, V. Y., Atkin, S. D., Gautron, L., Kliewer, S. A., & Mangelsdorf, D. J. (2013) · Nature Medicine

Hypothalamic control of reproductive hormonesFibroblast Growth Factor Research

Cited by 230

Hypoaminoacidemia underpins glucagon-mediated energy expenditure and weight loss

Hope, D. C. D., Hinds, C. E., Lopes, T., Vincent, M. L., Shrewsbury, J. V., Yu, A. T. C., Davies, I., Scott, R., Jones, B., Murphy, K. G., et al. (2022) · Cell Reports Medicine

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 32