Shi, Lei

Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 activity and NMDA receptor function.

Guo, D., Peng, Y., Wang, L., Sun, X., Wang, X., Liang, C., Yang, X., Li, S., Xu, J., Ye, W.-C., et al. (2021) · Molecular Psychiatry

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 102

Dock protein family in brain development and neurological disease

Shi, L. (2013) · Communicative & Integrative Biology

Protein Kinase Regulation and GTPase SignalingGenetics and Neurodevelopmental Disorders

Cited by 83

Rho GTPase Regulators and Effectors in Autism Spectrum Disorders: Animal Models and Insights for Therapeutics

Guo, D., Yang, X., & Shi, L. (2020) · Cells

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 73

The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics

Xiao, Y., Peng, Y., Wan, J., Tang, G., Chen, Y., Tang, J., Ye, W.-C., Ip, N. Y., & Shi, L. (2013) · Journal of Biological Chemistry

Axon Guidance and Neuronal SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 71

Two Autism/Dyslexia Linked Variations of DOCK4 Disrupt the Gene Function on Rac1/Rap1 Activation, Neurite Outgrowth, and Synapse Development

Huang, M., Liang, C., Li, S., Zhang, J., Guo, D., Zhao, B., Liu, Y., Peng, Y., Xu, J., Liu, W., et al. (2020) · Frontiers in Cellular Neuroscience

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 41

Regulating Rac in the Nervous System: Molecular Function and Disease Implication of Rac GEFs and GAPs

Bai, Y., Xiang, X., Liang, C., & Shi, L. (2015) · BioMed Research International

Protein Kinase Regulation and GTPase SignalingNeuroscience and Neuropharmacology Research

Cited by 40