Elsworth, John D.

Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

Abizaid, A., Liu, Z.-W., Andrews, Z. B., Shanabrough, M., Borok, E., Elsworth, J. D., Roth, R. H., Sleeman, M. W., Picciotto, M. R., Tschöp, M. H., et al. (2006) · Journal of Clinical Investigation

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

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Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing

Camell, C. D., Sander, J., Spadaro, O., Lee, A., Nguyen, K. Y., Wing, A., Goldberg, E. L., Youm, Y.-H., Brown, C. W., Elsworth, J., et al. (2017) · Nature

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 456

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

Miller, B. H., Zeier, Z., Xi, L., Lanz, T. A., Deng, S., Strathmann, J., Willoughby, D., Kenny, P. J., Elsworth, J. D., Lawrence, M. S., et al. (2012) · Proceedings of the National Academy of Sciences

Schizophrenia research and treatmentMicroRNA in disease regulation

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Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism

Andrews, Z. B., Erion, D., Beiler, R., Liu, Z.-W., Abizaid, A., Zigman, J., Elsworth, J. D., Savitt, J. M., DiMarchi, R., Tschöp, M., et al. (2009) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsRegulation of Appetite and Obesity

Cited by 289

Molecular and cellular reorganization of neural circuits in the human lineage

Sousa, A. M. M., Zhu, Y., Raghanti, M. A., Kitchen, R. R., Onorati, M., Tebbenkamp, A. T. N., Stutz, B., Meyer, K. A., Li, M., Kawasawa, Y. I., et al. (2017) · Science

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

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PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders

Jamwal, S., Blackburn, J. K., & Elsworth, J. D. (2021) · Pharmacology & Therapeutics

Peroxisome Proliferator-Activated ReceptorsMitochondrial Function and Pathology

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TMT, a predator odor, elevates mesoprefrontal dopamine metabolic activity and disrupts short-term working memory in the rat

Morrow, B. A., Roth, R. H., & Elsworth, J. D. (2000) · Brain Research Bulletin

Neurotransmitter Receptor Influence on BehaviorMemory and Neural Mechanisms

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Mesocortical dopamine neurons: High basal firing frequency predicts tyrosine dependence of dopamine synthesis

Tam, S. Y., Elsworth, J. D., Bradberry, C. W., & Roth, R. H. (1990) · Journal of Neural Transmission

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

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Low circulating levels of bisphenol‐A induce cognitive deficits and loss of asymmetric spine synapses in dorsolateral prefrontal cortex and hippocampus of adult male monkeys

Elsworth, J. D., Jentsch, J. D., Groman, S. M., Roth, R. H., Redmond, E. D., & Leranth, C. (2015) · Journal of Comparative Neurology

Effects and risks of endocrine disrupting chemicalsNeuroscience and Neuropharmacology Research

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