Bode, Johannes G.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 1,280

Hepatic acute phase proteins – Regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling

Bode, J. G., Albrecht, U., Häussinger, D., Heinrich, P. C., & Schaper, F. (2012) · European Journal of Cell Biology

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 379

LPS and TNFα induce SOCS3 mRNA and inhibit IL‐6‐induced activation of STAT3 in macrophages

Bode, J. G., Nimmesgern, A., Schmitz, J., Schaper, F., Schmitt, M., Frisch, W., Häussinger, D., Heinrich, P. C., & Graeve, L. (1999) · FEBS Letters

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 196

Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages

Haselow, K., Bode, J. G., Wammers, M., Ehlting, C., Keitel, V., Kleinebrecht, L., Schupp, A.-K., Häussinger, D., & Graf, D. (2013) · Journal of Leukocyte Biology

Immune Response and InflammationImmune cells in cancer

Cited by 164

Acute-phase protein synthesis: a key feature of innate immune functions of the liver

Ehlting, C., Wolf, S. D., & Bode, J. G. (2021) · Biological Chemistry

Biomarkers in Disease MechanismsAnimal health and immunology

Cited by 115

Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase

Qvartskhava, N., Lang, P. A., Görg, B., Pozdeev, V. I., Ortiz, M. P., Lang, K. S., Bidmon, H. J., Lang, E., Leibrock, C. B., Herebian, D., et al. (2015) · Proceedings of the National Academy of Sciences

Amino Acid Enzymes and MetabolismMetabolism and Genetic Disorders

Cited by 98

Glucocorticoids Increase Interleukin–6–Dependent Gene Induction by Interfering With the Expression of the Suppressor of Cytokine Signaling 3 Feedback Inhibitor

Dittrich, A., Khouri, C., Sackett, S. D., Ehlting, C., Böhmer, O., Albrecht, U., Bode, J. G., Trautwein, C., & Schaper, F. (2012) · Hepatology

Cytokine Signaling Pathways and InteractionsAdipokines, Inflammation, and Metabolic Diseases

Cited by 51

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib

Sobotta, S., Raue, A., Huang, X., Vanlier, J., Jünger, A., Bohl, S., Albrecht, U., Hahnel, M. J., Wolf, S., Mueller, N. S., et al. (2017) · Frontiers in Physiology

Cytokine Signaling Pathways and InteractionsGene Regulatory Network Analysis

Cited by 28