Brunello, Cecilia A.

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

Casarotto, P. C., Girych, M., Fred, S. M., Kovaleva, V., Moliner, R., Enkavi, G., Biojone, C., Cannarozzo, C., Sahu, M. P., Kaurinkoski, K., et al. (2021) · Cell

Treatment of Major DepressionNerve injury and regeneration

Cited by 663

Psychedelics promote plasticity by directly binding to BDNF receptor TrkB

Moliner, R., Girych, M., Brunello, C. A., Kovaleva, V., Biojone, C., Enkavi, G., Antenucci, L., Kot, E. F., Goncharuk, S. A., Kaurinkoski, K., et al. (2023) · Nature Neuroscience

Psychedelics and Drug StudiesTreatment of Major Depression

Cited by 478

Mechanisms of secretion and spreading of pathological tau protein

Brunello, C. A., Merezhko, M., Uronen, R.-L., & Huttunen, H. J. (2020) · Cellular and Molecular Life Sciences

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 304

Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2

Fred, S. M., Laukkanen, L., Brunello, C. A., Vesa, L., Göös, H., Cardon, I., Moliner, R., Maritzen, T., Varjosalo, M., Casarotto, P. C., et al. (2019) · Journal of Biological Chemistry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 52

Rethinking the role of TRKB in the action of antidepressants and psychedelics

Brunello, C. A., Cannarozzo, C., & Castrén, E. (2024) · Trends in Neurosciences

Treatment of Major DepressionNerve injury and regeneration

Cited by 31