Bozza, Marcelo T.

Characterization of Heme as Activator of Toll-like Receptor 4

Figueiredo, R. T., Fernandez, P. L., Mourao-Sa, D. S., Porto, B. N., Dutra, F. F., Alves, L. S., Oliveira, M. F., Oliveira, P. L., Graça-Souza, A. V., & Bozza, M. T. (2007) · Journal of Biological Chemistry

Immune Response and InflammationInflammasome and immune disorders

Cited by 576

Hemolysis-induced lethality involves inflammasome activation by heme

Dutra, F. F., Alves, L. S., Rodrigues, D., Fernandez, P. L., de Oliveira, R. B., Golenbock, D. T., Zamboni, D. S., & Bozza, M. T. (2014) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 353

Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation

Hottz, E. D., Lopes, J. F., Freitas, C., Valls-de-Souza, R., Oliveira, M. F., Bozza, M. T., Da Poian, A. T., Weyrich, A. S., Zimmerman, G. A., Bozza, F. A., et al. (2013) · Blood

Inflammasome and immune disordersMosquito-borne diseases and control

Cited by 348

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production

Fortes, G. B., Alves, L. S., de Oliveira, R., Dutra, F. F., Rodrigues, D., Fernandez, P. L., Souto-Padron, T., De Rosa, M. J., Kelliher, M., Golenbock, D., et al. (2012) · Blood

Cell death mechanisms and regulationImmune Response and Inflammation

Cited by 246

Heme Induces Neutrophil Migration and Reactive Oxygen Species Generation through Signaling Pathways Characteristic of Chemotactic Receptors

Porto, B. N., Alves, L. S., Fernández, P. L., Dutra, T. P., Figueiredo, R. T., Graça-Souza, A. V., & Bozza, M. T. (2007) · Journal of Biological Chemistry

Neutrophil, Myeloperoxidase and Oxidative MechanismsChemokine receptors and signaling

Cited by 161

Red alert: labile heme is an alarmin

Soares, M. P., & Bozza, M. T. (2016) · Current Opinion in Immunology

Immune Response and InflammationHemoglobin structure and function

Cited by 148

Monocyte Chemoattractant Protein-1/CC Chemokine Ligand 2 Controls Microtubule-Driven Biogenesis and Leukotriene B4-Synthesizing Function of Macrophage Lipid Bodies Elicited by Innate Immune Response

Pacheco, P., Vieira-de-Abreu, A., Gomes, R. N., Barbosa-Lima, G., Wermelinger, L. B., Maya-Monteiro, C. M., Silva, A. R., Bozza, M. T., Castro-Faria-Neto, H. C., Bandeira-Melo, C., et al. (2007) · The Journal of Immunology

Lipid metabolism and biosynthesisImmune Response and Inflammation

Cited by 103

Heme Amplifies the Innate Immune Response to Microbial Molecules through Spleen Tyrosine Kinase (Syk)-dependent Reactive Oxygen Species Generation*

Fernandez, P. L., Dutra, F. F., Alves, L., Figueiredo, R. T., Mourão-Sa, D., Fortes, G. B., Bergstrand, S., Lönn, D., Cevallos, R. R., Pereira, R. M. S., et al. (2010) · Journal of Biological Chemistry

Immune Response and InflammationNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 95

Soluble Factors Released by Toxoplasma gondii-Infected Astrocytes Down-Modulate Nitric Oxide Production by Gamma Interferon-Activated Microglia and Prevent Neuronal Degeneration

Rozenfeld, C., Martinez, R., Figueiredo, R. T., Bozza, M. T., Lima, F. R. S., Pires, A. L., Silva, P. M., Bonomo, A., Lannes-Vieira, J., De Souza, W., et al. (2003) · Infection and Immunity

Toxoplasma gondii Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 82

Binding of Glucuronoxylomannan to the CD14 Receptor in Human A549 Alveolar Cells Induces Interleukin-8 Production

Barbosa, F. M., Fonseca, F. L., Figueiredo, R. T., Bozza, M. T., Casadevall, A., Nimrichter, L., & Rodrigues, M. L. (2007) · Clinical and Vaccine Immunology

Fungal Infections and StudiesGlycosylation and Glycoproteins Research

Cited by 33

Cross-Talk between Macrophage Migration Inhibitory Factor and Eotaxin in Allergic Eosinophil Activation Forms Leukotriene C4–Synthesizing Lipid Bodies

Vieira-de-Abreu, A., Calheiros, A. S., Mesquita-Santos, F. P., Magalhães, E. S., Mourão-Sá, D., Castro-Faria-Neto, H. C., Bozza, M. T., Bandeira-Melo, C., & Bozza, P. T. (2011) · American Journal of Respiratory Cell and Molecular Biology

Macrophage Migration Inhibitory FactorAsthma and respiratory diseases

Cited by 28