Darmanis, Spyros

A survey of human brain transcriptome diversity at the single cell level

Darmanis, S., Sloan, S. A., Zhang, Y., Enge, M., Caneda, C., Shuer, L. M., Hayden Gephart, M. G., Barres, B. A., & Quake, S. R. (2015) · Proceedings of the National Academy of Sciences

Single-cell and spatial transcriptomicsNeurogenesis and neuroplasticity mechanisms

Cited by 1,401

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

The Tabula Muris Consortium, Almanzar, N., Antony, J., Baghel, A. S., Bakerman, I., Bansal, I., Barres, B. A., Beachy, P. A., Berdnik, D., Bilen, B., et al. (2020) · Nature

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 1,247

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

Li, Q., Cheng, Z., Zhou, L., Darmanis, S., Neff, N. F., Okamoto, J., Gulati, G., Bennett, M. L., Sun, L. O., Clarke, L. E., et al. (2019) · Neuron

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 1,129

Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells

Sloan, S. A., Darmanis, S., Huber, N., Khan, T. A., Birey, F., Caneda, C., Reimer, R., Quake, S. R., Barres, B. A., & Paşca, S. P. (2017) · Neuron

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 593

Single-cell proteomics enabled by next-generation sequencing or mass spectrometry

Bennett, H. M., Stephenson, W., Rose, C. M., & Darmanis, S. (2023) · Nature Methods

Advanced Proteomics Techniques and ApplicationsSingle-cell and spatial transcriptomics

Cited by 351

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells

Darmanis, S., Gallant, C. J., Marinescu, V. D., Niklasson, M., Segerman, A., Flamourakis, G., Fredriksson, S., Assarsson, E., Lundberg, M., Nelander, S., et al. (2016) · Cell Reports

Single-cell and spatial transcriptomicsAdvanced Proteomics Techniques and Applications

Cited by 219

Single-cell RNAseq reveals cell adhesion molecule profiles in electrophysiologically defined neurons

Földy, C., Darmanis, S., Aoto, J., Malenka, R. C., Quake, S. R., & Südhof, T. C. (2016) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchSingle-cell and spatial transcriptomics

Cited by 179

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction

Genshaft, A. S., Li, S., Gallant, C. J., Darmanis, S., Prakadan, S. M., Ziegler, C. G. K., Lundberg, M., Fredriksson, S., Hong, J., Regev, A., et al. (2016) · Genome Biology

Single-cell and spatial transcriptomicsAdvanced Proteomics Techniques and Applications

Cited by 175

Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Pálovics, R., Keller, A., Schaum, N., Tan, W., Fehlmann, T., Borja, M., Kern, F., Bonanno, L., Calcuttawala, K., Webber, J., et al. (2022) · Nature

Genetics, Aging, and Longevity in Model OrganismsSingle-cell and spatial transcriptomics

Cited by 153

Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade

Cruz Tleugabulova, M., Melo, S. P., Wong, A., Arlantico, A., Liu, M., Webster, J. D., Lau, J., Lechner, A., Corak, B., Hodgins, J. J., et al. (2024) · Nature Communications

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisLiver physiology and pathology

Cited by 38