Hohlfeld, Reinhard

Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction

Babbe, H., Roers, A., Waisman, A., Lassmann, H., Goebels, N., Hohlfeld, R., Friese, M., Schröder, R., Deckert, M., Schmidt, S., et al. (2000) · The Journal of Experimental Medicine

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 951

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice

Berer, K., Gerdes, L. A., Cekanaviciute, E., Jia, X., Xiao, L., Xia, Z., Liu, C., Klotz, L., Stauffer, U., Baranzini, S. E., et al. (2017) · Proceedings of the National Academy of Sciences

Multiple Sclerosis Research StudiesGut microbiota and health

Cited by 933

MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47

Junker, A., Krumbholz, M., Eisele, S., Mohan, H., Augstein, F., Bittner, R., Lassmann, H., Wekerle, H., Hohlfeld, R., & Meinl, E. (2009) · Brain

Multiple Sclerosis Research StudiesMicroRNA in disease regulation

Cited by 595

γ-secretase directly sheds the survival receptor BCMA from plasma cells

Laurent, S. A., Hoffmann, F. S., Kuhn, P.-H., Cheng, Q., Chu, Y., Schmidt-Supprian, M., Hauck, S. M., Schuh, E., Krumbholz, M., Rübsamen, H., et al. (2015) · Nature Communications

NF-κB Signaling PathwaysT-cell and B-cell Immunology

Cited by 377

Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study: A Randomized Clinical Trial

Kappos, L., Fox, R. J., Burcklen, M., Freedman, M. S., Havrdová, E. K., Hennessy, B., Hohlfeld, R., Lublin, F., Montalban, X., Pozzilli, C., et al. (2021) · JAMA Neurology

Multiple Sclerosis Research StudiesSphingolipid Metabolism and Signaling

Cited by 228

The role of the gut microbiota in multiple sclerosis

Correale, J., Hohlfeld, R., & Baranzini, S. E. (2022) · Nature Reviews Neurology

Gut microbiota and healthMultiple Sclerosis Research Studies

Cited by 207

Autoantibodies to MOG in a distinct subgroup of adult multiple sclerosis

Spadaro, M., Gerdes, L. A., Krumbholz, M., Ertl-Wagner, B., Thaler, F. S., Schuh, E., Metz, I., Blaschek, A., Dick, A., Brück, W., et al. (2016) · Neurology Neuroimmunology & Neuroinflammation

Multiple Sclerosis Research StudiesAutoimmune Neurological Disorders and Treatments

Cited by 206

Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration

Colombo, E., Cordiglieri, C., Melli, G., Newcombe, J., Krumbholz, M., Parada, L. F., Medico, E., Hohlfeld, R., Meinl, E., & Farina, C. (2012) · Journal of Experimental Medicine

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 146

The emerging role of microRNAs in multiple sclerosis

Junker, A., Hohlfeld, R., & Meinl, E. (2011) · Nature Reviews Neurology

Multiple Sclerosis Research StudiesMicroRNA in disease regulation

Cited by 129