Cheng, Xiaodong

Many paths to methyltransfer: a chronicle of convergence

Schubert, H. L., Blumenthal, R. M., & Cheng, X. (2003) · Trends in Biochemical Sciences

Cancer-related gene regulationEnzyme Structure and Function

Cited by 876

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

Horton, J. R., Upadhyay, A. K., Qi, H. H., Zhang, X., Shi, Y., & Cheng, X. (2010) · Nature Structural & Molecular Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 389

Protein lysine methyltransferase G9a acts on non-histone targets

Rathert, P., Dhayalan, A., Murakami, M., Zhang, X., Tamas, R., Jurkowska, R., Komatsu, Y., Shinkai, Y., Cheng, X., & Jeltsch, A. (2008) · Nature Chemical Biology

Cancer-related gene regulationEpigenetics and DNA Methylation

Cited by 347

Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA

Hashimoto, H., Wang, D., Horton, J. R., Zhang, X., Corces, V. G., & Cheng, X. (2017) · Molecular Cell

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 268

Independent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizures

Myrick, L. K., Deng, P.-Y., Hashimoto, H., Oh, Y. M., Cho, Y., Poidevin, M. J., Suhl, J. A., Visootsak, J., Cavalli, V., Jin, P., et al. (2015) · Proceedings of the National Academy of Sciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 133

Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

Zhao, J., Du, Y., Horton, J. R., Upadhyay, A. K., Lou, B., Bai, Y., Zhang, X., Du, L., Li, M., Wang, B., et al. (2011) · Proceedings of the National Academy of Sciences

14-3-3 protein interactionsProtein Kinase Regulation and GTPase Signaling

Cited by 105

Structural basis for Klf4 recognition of methylated DNA

Liu, Y., Olanrewaju, Y. O., Zheng, Y., Hashimoto, H., Blumenthal, R. M., Zhang, X., & Cheng, X. (2014) · Nucleic Acids Research

Kruppel-like factors researchEpigenetics and DNA Methylation

Cited by 99

Structural basis of human PR/SET domain 9 (PRDM9) allele C–specific recognition of its cognate DNA sequence

Patel, A., Zhang, X., Blumenthal, R. M., & Cheng, X. (2017) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 19