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Seizures in Fragile X Syndrome: Associations and Longitudinal Analysis of a Large Clinic-Based Cohort

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Cereblon Maintains Synaptic and Cognitive Function by Regulating BK Channel

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Potential Involvement of Impaired BKCa Channel Function in Sensory Defensiveness and Some Behavioral Disturbances Induced by Unfamiliar Environment in a Mouse Model of Fragile X Syndrome

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The Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic Paraplegias

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Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry

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Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome

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Altered synaptobrevin-II trafficking in neurons expressing a synaptophysin mutation associated with a severe neurodevelopmental disorder

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Excitability is increased in hippocampal CA1 pyramidal cells of Fmr1 knockout mice

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Differential regulation of BK channels by fragile X mental retardation protein

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CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory

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A 3′ untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA-binding protein HuR

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RNA Secondary Structure Modulates FMRP’s Bi-Functional Role in the MicroRNA Pathway

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Deletion of the KH1 Domain of <i>Fmr1</i> Leads to Transcriptional Alterations and Attentional Deficits in Rats

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New Insights Into the Role of Cav2 Protein Family in Calcium Flux Deregulation in Fmr1-KO Neurons

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Mouse models of fragile X-related disorders

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In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome

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FMRP-Driven Neuropathology in Autistic Spectrum Disorder and Alzheimer's disease: A Losing Game

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Potassium channelopathies associated with epilepsy-related syndromes and directions for therapeutic intervention

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Handling FMRP and its molecular partners: Structural insights into Fragile X Syndrome

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Fragile X mental retardation protein: from autism to neurodegenerative disease

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Synaptic vesicle dynamic changes in a model of fragile X

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Disruption of GpI mGluR-Dependent Cav2.3 Translation in a Mouse Model of Fragile X Syndrome

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Wnt/β-catenin pathway and cell adhesion deregulation in CSDE1-related intellectual disability and autism spectrum disorders

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Hippocampal neuronal subtypes develop abnormal dendritic arbors in the presence of Fragile X astrocytes

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Combination Therapy in Fragile X Syndrome; Possibilities and Pitfalls Illustrated by Targeting the mGluR5 and GABA Pathway Simultaneously

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FMRP Sustains Presynaptic Function via Control of Activity-Dependent Bulk Endocytosis

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FMRP regulates GABAA receptor channel activity to control signal integration in hippocampal granule cells

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Drosophila as a Model for Assessing the Function of RNA-Binding Proteins during Neurogenesis and Neurological Disease

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Structural and Functional Abnormalities in the Olfactory System of Fragile X Syndrome Models

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FMRP-PKA Activity Negative Feedback Regulates RNA Binding-Dependent Fibrillation in Brain Learning and Memory Circuitry

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Beyond Trinucleotide Repeat Expansion in Fragile X Syndrome: Rare Coding and Noncoding Variants in FMR1 and Associated Phenotypes

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FXS causing missense mutations disrupt FMRP granule formation, dynamics, and function

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Large‐conductance Ca2+‐activated K+channel activation by apical P2Y receptor agonists requires hydrocortisone in differentiated airway epithelium

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The quest for targeted therapy in fragile X syndrome

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Axonal and presynaptic FMRP: localization, signal, and functional implications

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Characterization of Fragile X Mental Retardation Protein expression in human nociceptors and their axonal projections to the spinal dorsal horn

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In Silico Analysis of FMR1 Gene Missense SNPs

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Kinase pathway inhibition restores PSD95 induction in neurons lacking fragile X mental retardation protein

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The loss of β adrenergic receptor mediated release potentiation in a mouse model of fragile X syndrome

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A missense variant in the nuclear export signal of the FMR1 gene causes intellectual disability

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Role of fragile X messenger ribonucleoprotein 1 in the pathophysiology of brain disorders: a glia perspective

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MiR-219 represses expression of dFMR1 in Drosophila melanogaster

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The SZT2 Interactome Unravels New Functions of the KICSTOR Complex

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Global ribosome profiling reveals that mutant huntingtin stalls ribosomes and represses protein synthesis independent of fragile X mental retardation proteinPreprint

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Therapeutic efficacy of the BKCa channel opener chlorzoxazone in a mouse model of Fragile X syndrome

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Presentation of a recurrent FMR1 missense mutation (R138Q) in an affected female

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Reversal of behavioural phenotype by the cannabinoid-like compound VSN16R in fragile X syndrome mice

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Neuronal potassium channel activity triggers initiation of mRNA translation through binding of translation regulators

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Dynamic balance of excitation and inhibition rapidly modulates spike probability and precision in feed-forward hippocampal circuits

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From Discovery to Innovative Translational Approaches in 80 Years of Fragile X Syndrome Research

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Molecular Profiling of Mouse Models of Loss or Gain of Function of the KCNT1 (Slack) Potassium Channel and Antisense Oligonucleotide Treatment

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Convergent depression of activity-dependent bulk endocytosis in rodent models of autism spectrum disorder

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Recurrent missense variant in the nuclear export signal of FMR1 associated with FXS-like phenotype including intellectual disability, ASD, facial abnormalities

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Screening for FMR1 expanded alleles in patients with Autism Spectrum Disorders in Manaus, Northern Brazil

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Large-conductance calcium-activated potassium channel haploinsufficiency leads to sensory deficits in the visual system: a case report

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Folding Mechanism and Aggregation Propensity of the KH0 Domain of FMRP and Its R138Q Pathological Variant

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A Species-Correlated Transitional Residue D132 on Human FMRP Plays a Role in Nuclear Localization via an RNA-Dependent Interaction With PABP1

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Epidemiology of Fragile X Syndrome

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Fragile X Syndrome Genetics

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Loss of the KH1 domain of FMR1 in humans due to a synonymous variant causes global developmental retardation

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RNA and Protein Targets of FMRP

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FMRP association with and regulation of Fragile X granules exhibit circuit-dependent requirements for the KH2 RNA binding domainPreprint

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FMR1 genetically interacts with DISC1 to regulate glutamatergic synaptogenesis

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FMR1 KH0-KH1 domains coordinate m6A binding and phase separation in Fragile X syndrome

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Systematic mapping of fragile X granules in the mouse brain reveals a potential role for presynaptic FMRP in sensorimotor functions

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Pathophysiological consequences of a Fragile X missense mutation

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Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation

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Altered synaptic plasticity in a mouse model of fragile X mental retardation

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Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure

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