Gray, Joe W.

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Verhaak, R. G. W., Hoadley, K. A., Purdom, E., Wang, V., Qi, Y., Wilkerson, M. D., Miller, C. R., Ding, L., Golub, T., Mesirov, J. P., et al. (2010) · Cancer Cell

Glioma Diagnosis and TreatmentCancer Genomics and Diagnostics

Cited by 7,575

The consensus molecular subtypes of colorectal cancer

Guinney, J., Dienstmann, R., Wang, X., de Reyniès, A., Schlicker, A., Soneson, C., Marisa, L., Roepman, P., Nyamundanda, G., Angelino, P., et al. (2015) · Nature Medicine

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

Cited by 5,170

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

Collisson, E. A., Sadanandam, A., Olson, P., Gibb, W. J., Truitt, M., Gu, S., Cooc, J., Weinkle, J., Kim, G. E., Jakkula, L., et al. (2011) · Nature Medicine

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 1,967

Induction of tumors in mice by genomic hypomethylation

Gaudet, F., Hodgson, J. G., Eden, A., Jackson-Grusby, L., Dausman, J., Gray, J. W., Leonhardt, H., & Jaenisch, R. (2003) · Science

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 1,499

An integrative genomic and proteomic analysis of pik3ca, pten, and akt mutations in breast cancer.

Stemke-Hale, K., Gonzalez-Angulo, A. M., Lluch, A., Neve, R. M., Kuo, W.-L., Davies, M., Carey, M., Hu, Z., Guan, Y., Sahin, A., et al. (2008) · Cancer Research

PI3K/AKT/mTOR signaling in cancerBreast Cancer Treatment Studies

Cited by 1,054

A colorectal cancer classification system that associates cellular phenotype and responses to therapy

Sadanandam, A., Lyssiotis, C. A., Homicsko, K., Collisson, E. A., Gibb, W. J., Wullschleger, S., Ostos, L. C. G., Lannon, W. A., Grotzinger, C., Del Rio, M., et al. (2013) · Nature Medicine

Colorectal Cancer Treatments and StudiesGene expression and cancer classification

Cited by 960

Chromosome aberrations in solid tumors

Albertson, D. G., Collins, C., McCormick, F., & Gray, J. W. (2003) · Nature Genetics

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 812

Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene

Albertson, D. G., Ylstra, B., Segraves, R., Collins, C., Dairkee, S. H., Kowbel, D., Kuo, W.-L., Gray, J. W., & Pinkel, D. (2000) · Nature Genetics

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 589

Glutamine Sensitivity Analysis Identifies the xCT Antiporter as a Common Triple-Negative Breast Tumor Therapeutic Target

Timmerman, L. A., Holton, T., Yuneva, M., Louie, R. J., Padró, M., Daemen, A., Hu, M., Chan, D. A., Ethier, S. P., van ‘t Veer, L. J., et al. (2013) · Cancer Cell

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 573

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization

Kallioniemi, O. P., Kallioniemi, A., Kurisu, W., Thor, A., Chen, L. C., Smith, H. S., Waldman, F. M., Pinkel, D., & Gray, J. W. (1992) · Proceedings of the National Academy of Sciences

HER2/EGFR in Cancer ResearchBreast Cancer Treatment Studies

Cited by 555

Molecular Characterization of the Cytotoxic Mechanism of Multiwall Carbon Nanotubes and Nano-Onions on Human Skin Fibroblast

Ding, L., Stilwell, J., Zhang, T., Elboudwarej, O., Jiang, H., Selegue, J. P., Cooke, P. A., Gray, J. W., & Chen, F. F. (2005) · Nano Letters

Graphene and Nanomaterials ApplicationsNanoparticles: synthesis and applications

Cited by 549

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

Keenan, A. B., Jenkins, S. L., Jagodnik, K. M., Koplev, S., He, E., Torre, D., Wang, Z., Dohlman, A. B., Silverstein, M. C., Lachmann, A., et al. (2018) · Cell Systems

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 423

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Lovci, M. T., Ghanem, D., Marr, H., Arnold, J., Gee, S., Parra, M., Liang, T. Y., Stark, T. J., Gehman, L. T., Hoon, S., et al. (2013) · Nature Structural & Molecular Biology

RNA Research and SplicingRNA regulation and disease

Cited by 385

In situ analyses of genome instability in breast cancer

Chin, K., de Solorzano, C. O., Knowles, D., Jones, A., Chou, W., Rodriguez, E. G., Kuo, W.-L., Ljung, B.-M., Chew, K., Myambo, K., et al. (2004) · Nature Genetics

Telomeres, Telomerase, and SenescenceCancer Genomics and Diagnostics

Cited by 361

β1 Integrin Inhibitory Antibody Induces Apoptosis of Breast Cancer Cells, Inhibits Growth, and Distinguishes Malignant from Normal Phenotype in Three Dimensional Cultures and In vivo

Park, C. C., Zhang, H., Pallavicini, M., Gray, J. W., Baehner, F., Park, C. J., & Bissell, M. J. (2006) · Cancer Research

Cell Adhesion Molecules ResearchCancer Cells and Metastasis

Cited by 326

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

Hodgson, G., Hager, J. H., Volik, S., Hariono, S., Wernick, M., Moore, D., Albertson, D. G., Pinkel, D., Collins, C., Hanahan, D., et al. (2001) · Nature Genetics

Genomic variations and chromosomal abnormalitiesPancreatic function and diabetes

Cited by 294

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution

Cheng, J. B., Sedgewick, A. J., Finnegan, A. I., Harirchian, P., Lee, J., Kwon, S., Fassett, M. S., Golovato, J., Gray, M., Ghadially, R., et al. (2018) · Cell Reports

Single-cell and spatial transcriptomicsDermatology and Skin Diseases

Cited by 284

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

Nan, X., Tamgüney, T. M., Collisson, E. A., Lin, L.-J., Pitt, C., Galeas, J., Lewis, S., Gray, J. W., McCormick, F., & Chu, S. (2015) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 273

Modeling tumor phenotypes in vitro with three-dimensional bioprinting

Langer, E. M., Allen-Petersen, B. L., King, S. M., Kendsersky, N. D., Turnidge, M. A., Kuziel, G. M., Riggers, R., Samatham, R., Amery, T. S., Jacques, S. L., et al. (2019) · Cell Reports

3D Printing in Biomedical ResearchCellular Mechanics and Interactions

Cited by 256

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Risom, T., Langer, E. M., Chapman, M. P., Rantala, J., Fields, A. J., Boniface, C., Alvarez, M. J., Kendsersky, N. D., Pelz, C. R., Johnson-Camacho, K., et al. (2018) · Nature Communications

Cancer Cells and MetastasisBreast Cancer Treatment Studies

Cited by 174

TBX3 and Its Isoform TBX3+2a Are Functionally Distinctive in Inhibition of Senescence and Are Overexpressed in a Subset of Breast Cancer Cell Lines

Fan, W., Huang, X., Chen, C., Gray, J., & Huang, T. (2004) · Cancer Research

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 136

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

Niepel, M., Hafner, M., Mills, C. E., Subramanian, K., Williams, E. H., Chung, M., Gaudio, B., Barrette, A. M., Stern, A. D., Hu, B., et al. (2019) · Cell Systems

Scientific Computing and Data ManagementAnimal testing and alternatives

Cited by 133

Precision Medicine in Pancreatic Disease—Knowledge Gaps and Research Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop

Lowe, M. E., Andersen, D. K., Caprioli, R. M., Choudhary, J., Cruz-Monserrate, Z., Dasyam, A. K., Forsmark, C. E., Gorelick, F. S., Gray, J. W., Haupt, M., et al. (2019) · Pancreas

Pancreatitis Pathology and TreatmentPancreatic and Hepatic Oncology Research

Cited by 15

The morphologies of breast cancer cell lines in three‐dimensional assays correlate with their profiles of gene expression

Kenny, P. A., Lee, G. Y., Myers, C. A., Neve, R. M., Semeiks, J. R., Spellman, P. T., Lorenz, K., Lee, E. H., Barcellos-Hoff, M. H., Petersen, O. W., et al. (2007) · Molecular Oncology

Cancer Cells and MetastasisCellular Mechanics and Interactions

Cited by 2