Kanaan, Nicholas M.

Tau Kinetics in Neurons and the Human Central Nervous System

Sato, C., Barthélemy, N. R., Mawuenyega, K. G., Patterson, B. W., Gordon, B. A., Jockel-Balsarotti, J., Sullivan, M., Crisp, M. J., Kasten, T., Kirmess, K. M., et al. (2018) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 586

Liquid-liquid phase separation induces pathogenic tau conformations in vitro

Kanaan, N. M., Hamel, C., Grabinski, T., & Combs, B. (2020) · Nature Communications

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 397

Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo

Apicco, D. J., Ash, P. E. A., Maziuk, B., LeBlang, C., Medalla, M., Al Abdullatif, A., Ferragud, A., Botelho, E., Ballance, H. I., Dhawan, U., et al. (2018) · Nature Neuroscience

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 281

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

Duffy, M. F., Collier, T. J., Patterson, J. R., Kemp, C. J., Luk, K. C., Tansey, M. G., Paumier, K. L., Kanaan, N. M., Fischer, D. L., Polinski, N. K., et al. (2018) · Journal of Neuroinflammation

Parkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 197

Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy

Jiang, L., Lin, W., Zhang, C., Ash, P. E. A., Verma, M., Kwan, J., van Vliet, E., Yang, Z., Cruz, A. L., Boudeau, S., et al. (2021) · Molecular Cell

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 177

TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau

Ash, P. E. A., Lei, S., Shattuck, J., Boudeau, S., Carlomagno, Y., Medalla, M., Mashimo, B. L., Socorro, G., Al-Mohanna, L. F. A., Jiang, L., et al. (2021) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsRNA Research and Splicing

Cited by 159

Tau Kinetics in Neurons and the Human Central Nervous System

Sato, C., Barthélemy, N. R., Mawuenyega, K. G., Patterson, B. W., Gordon, B. A., Jockel-Balsarotti, J., Sullivan, M., Crisp, M. J., Kasten, T., Kirmess, K. M., et al. (2018) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 154

Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys

Kordower, J. H., Kanaan, N. M., Chu, Y., Suresh Babu, R., Stansell, J., Terpstra, B. T., Sortwell, C. E., Steece-Collier, K., & Collier, T. J. (2006) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 141

Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease

Vana, L., Kanaan, N. M., Ugwu, I. C., Wuu, J., Mufson, E. J., & Binder, L. I. (2011) · The American Journal of Pathology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 138

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport

Kanaan, N. M., Morfini, G., Pigino, G., LaPointe, N. E., Andreadis, A., Song, Y., Leitman, E., Binder, L. I., & Brady, S. T. (2012) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 134

Axonal degeneration in tauopathies: disease relevance and underlying mechanisms

Kneynsberg, A., Combs, B., Christensen, K., Morfini, G., & Kanaan, N. M. (2017) · Frontiers in Neuroscience

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 102

Rho-kinase ROCK inhibitors reduce oligomeric tau protein

Hamano, T., Shirafuji, N., Yen, S.-H., Yoshida, H., Kanaan, N. M., Hayashi, K., Ikawa, M., Yamamura, O., Fujita, Y., Kuriyama, M., et al. (2020) · Neurobiology of Aging

Alzheimer's disease research and treatmentsProtein Kinase Regulation and GTPase Signaling

Cited by 76

Neuronal and Glial Distribution of Tau Protein in the Adult Rat and Monkey

Kanaan, N. M., & Grabinski, T. (2021) · Frontiers in Molecular Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 46

Central role for p62/SQSTM1 in the elimination of toxic tau species in a mouse model of tauopathy

Ono, M., Komatsu, M., Ji, B., Takado, Y., Shimojo, M., Minamihisamatsu, T., Warabi, E., Yanagawa, T., Matsumoto, G., Aoki, I., et al. (2022) · Aging Cell

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 45

Tau here, tau there, tau almost everywhere: Clarifying the distribution of tau in the adult CNS

Kanaan, N. M. (2024) · Cytoskeleton

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 15