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Writers, readers, and erasers RNA modifications and drug resistance in cancer

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RNA methylation influences TDP43 binding and disease pathogenesis in models of amyotrophic lateral sclerosis and frontotemporal dementia

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Tau interactome and RNA binding proteins in neurodegenerative diseases

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Conserved reduction of m 6 A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts

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CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

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N6‐methyladenosine (m6A) modification in gynecological malignancies

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Alzheimer’s disease and related tauopathies: disorders of disrupted neuronal identity

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Identification of circRNAs linked to Alzheimer's disease and related dementias

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Aberrant splicing in Huntington’s disease accompanies disrupted TDP-43 activity and altered m6A RNA modification

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The Role of Retrotransposons and Endogenous Retroviruses in Age-Dependent Neurodegenerative Disorders

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Neuronal nuclear tau and neurodegeneration

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RNA induces unique tau strains and stabilizes Alzheimer’s disease seeds

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Epitranscriptomic dynamics in brain development and disease

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RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation

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m6A RNA methylation regulates mitochondrial function

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Role of N6-methyladenosine modification in central nervous system diseases and related therapeutic agents

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Disrupting pathologic phase transitions in neurodegeneration

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Aggregation, Transmission, and Toxicity of the Microtubule-Associated Protein Tau: A Complex Comprehension

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Stress granules: emerging players in neurodegenerative diseases

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Dysregulation of RNA modification systems in clinical populations with neurocognitive disorders

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Synaptic Disruption by Soluble Oligomers in Patients with Alzheimer’s and Parkinson’s Disease

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A new perspective on Alzheimer’s disease: m6A modification

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Proteostasis Deregulation in Neurodegeneration and Its Link with Stress Granules: Focus on the Scaffold and Ribosomal Protein RACK1

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Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions

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An integrative systems-biology approach defines mechanisms of Alzheimer’s disease neurodegeneration

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Emerging Mutual Regulatory Roles between m6A Modification and microRNAs

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Single-cell m6A profiling in the mouse brain uncovers cell type-specific RNA methylomes and age-dependent differential methylation

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Emerging Roles for DNA 6mA and RNA m6A Methylation in Mammalian Genome

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Biomolecular condensates and disease pathogenesis

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Mid-infrared chemical imaging of intracellular tau fibrils using fluorescence-guided computational photothermal microscopy

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Structural and functional damage to neuronal nuclei caused by extracellular tau oligomers

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Application of Optogenetics in Neurodegenerative Diseases

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The Landscape of m6A Regulators in Multiple Brain Regions of Alzheimer’s Disease

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Virus-Induced Membrane Fusion in Neurodegenerative Disorders

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Decoding the interplay between m 6 A modification and stress granule stability by live-cell imaging

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Domain-specific modulatory effects of phosphomimetic substitutions on liquid-liquid phase separation of tau protein

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VCP regulates early tau seed amplification via specific cofactors

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Development of a brain-penetrant G9a methylase inhibitor to target Alzheimer’s disease-associated proteopathology

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Chaperoning of specific tau structure by immunophilin FKBP12 regulates the neuronal resilience to extracellular stress

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HNRNPA2B1 and HNRNPR stabilize ASCL1 in an m6A-dependent manner to promote neuroblastoma progression

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Exploring the Diverse Functional and Regulatory Consequences of Alternative Splicing in Development and Disease

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The N6 ‐methyladenosine RNA landscape in the aged mouse hippocampus

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m6A mRNA methylation in human brain is disrupted in Lewy body disorders

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C9orf72 poly-PR forms anisotropic condensates causative of nuclear TDP-43 pathology

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hnRNP A1 , hnRNP A2B1 , and hnRNP K are dysregulated in tauopathies, but do not colocalize with tau pathology

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Tau, RNA, and RNA-Binding Proteins: Complex Interactions in Health and Neurodegenerative Diseases

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RNA-binding protein dysfunction in neurodegeneration

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β-amyloid accumulation enhances microtubule associated protein tau pathology in an APPNL-G-F/MAPTP301S mouse model of Alzheimer’s disease

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Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies

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Pathogenic tau induces an adaptive elevation in mRNA translation rate at early stages of disease

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Intracellular tau fragment droplets serve as seeds for tau fibrils

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Tau mRNA Metabolism in Neurodegenerative Diseases: A Tangle Journey

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The complex roles of m6A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases

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Liquid-liquid phase separation of tau and α-synuclein: A new pathway of overlapping neuropathologies

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F-box/LRR-repeat protein 12 reorchestrated microglia to inhibit scarring and achieve adult spinal cord injury repair

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Phase separation of the microtubule-associated protein tau

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Alzheimer’s Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins

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Discovery of a selective YTHDC1 inhibitor that targets acute myeloid leukemiaPreprint

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Aberrant splicing in Huntington’s disease via disrupted TDP-43 activity accompanied by altered m6A RNA modification

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Deciphering the regulatory landscape of enhancer RNAs in health and disease

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Progress in precision drug delivery systems for neurodegenerative diseases with muscle atrophy

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Comprehensive transcript-level analysis reveals transcriptional reprogramming during the progression of Alzheimer’s disease

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Live-cell visualization of tau aggregation in human neurons

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Gut microbe-derived betulinic acid alleviates sepsis-induced acute liver injury by inhibiting macrophage NLRP3 inflammasome in mice

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Human microglia differentially respond to β‐amyloid, tau, and combined Alzheimer's disease pathologies in vivo

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Visualizing liquid-liquid phase separation and protein aggregates

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O-GlcNAc modification differentially regulates microtubule binding and pathological conformations of tau isoforms in vitro

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Analysis of human brain RNA-seq data reveals combined effects of 4 types of RNA modifications and 18 types of programmed cell death on Alzheimer’s disease

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Lipoprotein Metabolism, Protein Aggregation, and Alzheimer’s Disease: A Literature Review

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Oligomeric, phosphorylated, and truncated tau and spliceosome pathology within the entorhinal–hippocampal connectome across stages of Alzheimer's disease

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Knockdown of RUVBL2 improves hnRNPA2 / B1 ‐stress granules dynamics to inhibit perioperative neurocognitive disorders in aged mild cognitive impairment rats

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Mettl3 regulates the pathogenesis of Alzheimer’s disease via fine-tuning Lingo2

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m5C RNA methylation: a potential mechanism for infectious Alzheimer’s disease

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Neuromodulatory role and therapeutic potential of N6-methyladenosine RNA methylation in neurodegenerative diseases

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Tubulin transforms Tau and α-synuclein condensates from pathological to physiological

Lucas, L., Tsoi, P. S., Quan, M. D., Choi, K., Ferreon, J. C., & Ferreon, A. C. M. (2026) · Nature Communications · doi:10.1038/s41467-026-69618-3 · Cited by 11 · see citing works

HNRNPA2B1 Demonstrates Diagnostic and Prognostic Values Based on Pan-Cancer Analyses

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Molecular Visualization of Neuronal TDP43 Pathology In SituPreprint

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Diverse influences on tau aggregation and implications for disease progressionPreprint

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Cell redistribution of G quadruplex‐structured DNA is associated with morphological changes of nuclei and nucleoli in neurons during tau pathology progression

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Pathogenic oligomeric Tau alters neuronal RNA processes through the formation of nuclear heteromeric amyloids with RNA-binding protein Musashi1

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The interactome of tau phosphorylated at T217 in Alzheimer’s disease human brain tissue

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Innate immune sensors for detecting nucleic acids during infection

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Recent advances in the interplay between stress granules and m6A RNA modification

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Mechanisms linking cerebrovascular dysfunction and tauopathy: Adding a layer of epiregulatory complexity

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METTL3-Driven m6A Epigenetic Remodeling of lncRNA-AU020206 Stabilizes SLC7A11 via YTHDC2 Attenuates Apoptosis and Ferroptosis in Cerebral Ischemia/Reperfusion Injury

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A Complex Containing HNRNPA2B1 and N 6 -methyladenosine Modified Transcripts Mediates Actions of Toxic Tau OligomersPreprint

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HNRNPA2B1 Mediates the Association of Oligomeric Tau with N 6-Methyladenosine and NeurodegenerationPreprint

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Tau oligomers are linked to m6A-RNA

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Amyloid-beta increases MBP and MOBP translation in oligodendrocytes through dysregulation of hnRNP A2 dependent RNA dynamicsPreprint

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