Pearson, Helen B.
The University of Melbourne · Peter MacCallum Cancer Centre
5 papers on CoChatORCID 0000-0002-3284-0843
Most cited papers
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Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation
Liu, D. S., Duong, C. P., Haupt, S., Montgomery, K. G., House, C. M., Azar, W. J., Pearson, H. B., Fisher, O. M., Read, M., Guerra, G. R., et al. (2017) · Nature Communications
Cancer-related Molecular PathwaysSulfur Compounds in Biology
Cited by 321
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SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia
Pearson, H. B., Perez-Mancera, P. A., Dow, L. E., Ryan, A., Tennstedt, P., Bogani, D., Elsum, I., Greenfield, A., Tuveson, D. A., Simon, R., et al. (2011) · Journal of Clinical Investigation
Prostate Cancer Treatment and ResearchProtein Kinase Regulation and GTPase Signaling
Cited by 185
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Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland
Godde, N. J., Sheridan, J. M., Smith, L. K., Pearson, H. B., Britt, K. L., Galea, R. C., Yates, L. L., Visvader, J. E., & Humbert, P. O. (2014) · PLoS Genetics
Developmental Biology and Gene RegulationCancer Cells and Metastasis
Cited by 60
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Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo
Elsum, I. A., Yates, L. L., Pearson, H. B., Phesse, T. J., Long, F., O'Donoghue, R., Ernst, M., Cullinane, C., & Humbert, P. O. (2014) · Oncogene
Protein Kinase Regulation and GTPase SignalingLung Cancer Treatments and Mutations
Cited by 60
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The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis
Pearson, H. B., McGlinn, E., Phesse, T. J., Schlüter, H., Srikumar, A., Gödde, N. J., Woelwer, C. B., Ryan, A., Phillips, W. A., Ernst, M., et al. (2015) · Molecular Cancer
Skin and Cellular Biology ResearchDevelopmental Biology and Gene Regulation
Cited by 39
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