Pun, Frank W.

AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor

Ren, F., Ding, X., Zheng, M., Korzinkin, M., Cai, X., Zhu, W., Mantsyzov, A., Aliper, A., Aladinskiy, V., Cao, Z., et al. (2023) · Chemical Science

Computational Drug Discovery MethodsProtein Degradation and Inhibitors

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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models

Ren, F., Aliper, A., Chen, J., Zhao, H., Rao, S., Kuppe, C., Ozerov, I. V., Zhang, M., Witte, K., Kruse, C., et al. (2025) · Nature Biotechnology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisComputational Drug Discovery Methods

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AI-powered therapeutic target discovery

Pun, F. W., Ozerov, I. V., & Zhavoronkov, A. (2023) · Trends in Pharmacological Sciences

Computational Drug Discovery MethodsProtein Degradation and Inhibitors

Cited by 341

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Pun, F. W., Liu, B. H. M., Long, X., Leung, H. W., Leung, G. H. D., Mewborne, Q. T., Gao, J., Shneyderman, A., Ozerov, I. V., Wang, J., et al. (2022) · Frontiers in Aging Neuroscience

Amyotrophic Lateral Sclerosis ResearchComputational Drug Discovery Methods

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Imprinting in the schizophrenia candidate gene GABRB2 encoding GABAA receptor β2 subunit

Pun, F. W., Zhao, C., Lo, W.-S., Ng, S.-K., Tsang, S.-Y., Nimgaonkar, V, Chung, W. S., Ungvari, G. S., & Xue, H. (2011) · Molecular Psychiatry

Genetic Syndromes and ImprintingSchizophrenia research and treatment

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TNIK’s emerging role in cancer, metabolism, and age-related diseases

Ewald, C. Y., Pulous, F. E., Lok, S. W. Y., Pun, F. W., Aliper, A., Ren, F., & Zhavoronkov, A. (2024) · Trends in Pharmacological Sciences

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 27

DORA AI Scientist: Multi-agent Virtual Research Team for Scientific Exploration Discovery and Automated Report Generation

Naumov, V., Zagirova, D., Lin, S., Xie, Y., Gou, W., Urban, A., Tikhonova, N., Alawi, K., Durymanov, M., Galkin, F., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory)

Academic Writing and PublishingArtificial Intelligence Applications

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