Humphrey, Mary Beth

Cutting Edge: Inhibition of TLR and FcR Responses in Macrophages by Triggering Receptor Expressed on Myeloid Cells (TREM)-2 and DAP12

Hamerman, J. A., Jarjoura, J. R., Humphrey, M. B., Nakamura, M. C., Seaman, W. E., & Lanier, L. L. (2006) · The Journal of Immunology

Immune Response and InflammationInflammation biomarkers and pathways

Cited by 440

Glucocorticoid-Induced Osteoporosis

Buckley, L., & Humphrey, M. B. (2018) · New England Journal of Medicine

Bone health and osteoporosis researchBone health and treatments

Cited by 438

TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1

Peng, Q., Malhotra, S., Torchia, J. A., Kerr, W. G., Coggeshall, K. M., & Humphrey, M. B. (2010) · Science Signaling

Bone Metabolism and DiseasesPhagocytosis and Immune Regulation

Cited by 413

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

Adrianto, I., Wen, F., Templeton, A., Wiley, G., King, J. B., Lessard, C. J., Bates, J. S., Hu, Y., Kelly, J. A., Kaufman, K. M., et al. (2011) · Nature Genetics

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

Cited by 279

TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function

Humphrey, M. B., Daws, M. R., Spusta, S. C., Niemi, E. C., Torchia, J. A., Lanier, L. L., Seaman, W. E., & Nakamura, M. C. (2006) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesPhagocytosis and Immune Regulation

Cited by 162

The TREM2-DAP12 signaling pathway in Nasu–Hakola disease: a molecular genetics perspective

Humphrey, M. B., Xing, J., & Titus, A. (2015) · Research and Reports in Biochemistry

Neuroinflammation and Neurodegeneration MechanismsBone Metabolism and Diseases

Cited by 77

SHIP inhibition mediates select TREM2-induced microglial functions

Ramakrishnan, G. S., Berry, W. L., Pacherille, A., Kerr, W. G., Chisholm, J. D., Pedicone, C., & Humphrey, M. B. (2024) · Molecular Immunology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 17