Cowley, Shaun M.

The Myc/Max/Mad Network and the Transcriptional Control of Cell Behavior

Grandori, C., Cowley, S. M., James, L. P., & Eisenman, R. N. (2000) · Annual Review of Cell and Developmental Biology

Genomics and Chromatin DynamicsCancer-related Molecular Pathways

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Enhancer decommissioning by LSD1 during embryonic stem cell differentiation

Whyte, W. A., Bilodeau, S., Orlando, D. A., Hoke, H. A., Frampton, G. M., Foster, C. T., Cowley, S. M., & Young, R. A. (2012) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 602

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Millard, C. J., Watson, P. J., Celardo, I., Gordiyenko, Y., Cowley, S. M., Robinson, C. V., Fairall, L., & Schwabe, J. W. R. (2013) · Molecular Cell

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 396

The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts

Kelly, R. D. W., & Cowley, S. M. (2013) · Biochemical Society Transactions

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 297

Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Watson, P. J., Millard, C. J., Riley, A. M., Robertson, N. S., Wright, L. C., Godage, H. Y., Cowley, S. M., Jamieson, A. G., Potter, B. V. L., & Schwabe, J. W. R. (2016) · Nature Communications

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 244

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo

Kelly, R. D. W., Chandru, A., Watson, P. J., Song, Y., Blades, M., Robertson, N. S., Jamieson, A. G., Schwabe, J. W. R., & Cowley, S. M. (2018) · Scientific Reports

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 138

PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes

Smalley, J. P., Adams, G. E., Millard, C. J., Song, Y., Norris, J. K. S., Schwabe, J. W. R., Cowley, S. M., & Hodgkinson, J. T. (2020) · Chemical Communications

Protein Degradation and InhibitorsHistone Deacetylase Inhibitors Research

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The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure

Turnbull, R. E., Fairall, L., Saleh, A., Kelsall, E., Morris, K. L., Ragan, T. J., Savva, C. G., Chandru, A., Millard, C. J., Makarova, O. V., et al. (2020) · Nature Communications

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

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Mutations on the surface of HDAC1 reveal molecular determinants of specific complex assembly and their requirement for gene regulation

Alshehri, A., Baker, I.-M., English, D. M., Fairall, L., Collins, M. O., Schwabe, J. W., & Cowley, S. M. (2025) · Nucleic Acids Research

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 5

Mutations on the surface of HDAC1 reveal molecular determinants of specific complex assembly and their requirement for gene regulation

Alshehri, A., Baker, I.-M., English, D. M., Fairall, L., Collins, M. O., Schwabe, J. W. R., & Cowley, S. M. (2025) · Nucleic Acids Research

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 5