Atadja, Peter

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

Gao, H., Korn, J. M., Ferretti, S., Monahan, J. E., Wang, Y., Singh, M., Zhang, C., Schnell, C., Yang, G., Zhang, Y., et al. (2015) · Nature Medicine

Cancer Cells and MetastasisCancer Genomics and Diagnostics

Cited by 1,393

Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90

Bali, P., Pranpat, M., Bradner, J., Balasis, M., Fiskus, W., Guo, F., Rocha, K., Kumaraswamy, S., Boyapalle, S., Atadja, P., et al. (2005) · Journal of Biological Chemistry

Heat shock proteins researchHistone Deacetylase Inhibitors Research

Cited by 755

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

Gao, L., Cueto, M. A., Asselbergs, F., & Atadja, P. (2002) · Journal of Biological Chemistry

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 744

The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

Villagra, A., Cheng, F., Wang, H.-W., Suarez, I., Glozak, M., Maurin, M., Nguyen, D., Wright, K. L., Atadja, P. W., Bhalla, K., et al. (2009) · Nature Immunology

T-cell and B-cell ImmunologyHistone Deacetylase Inhibitors Research

Cited by 455

An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED

Qi, W., Zhao, K., Gu, J., Huang, Y., Wang, Y., Zhang, H., Zhang, M., Zhang, J., Yu, Z., Li, L., et al. (2017) · Nature Chemical Biology

Epigenetics and DNA MethylationCancer-related gene regulation

Cited by 316

Increased activity of p53 in senescing fibroblasts

Atadja, P., Wong, H., Garkavtsev, I., Veillette, C., & Riabowol, K. (1995) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 308

Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors

Whitehead, L., Dobler, M. R., Radetich, B., Zhu, Y., Atadja, P. W., Claiborne, T., Grob, J. E., McRiner, A., Pancost, M. R., Patnaik, A., et al. (2011) · Bioorganic & Medicinal Chemistry

Histone Deacetylase Inhibitors ResearchEnzyme function and inhibition

Cited by 164

The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph− acute lymphoblastic leukemia cells

Scuto, A., Kirschbaum, M., Kowolik, C., Kretzner, L., Juhasz, A., Atadja, P., Pullarkat, V., Bhatia, R., Forman, S., Yen, Y., et al. (2008) · Blood

Histone Deacetylase Inhibitors ResearchAcute Lymphoblastic Leukemia research

Cited by 141

IGF-1 suppresses Bim expression in multiple myeloma via epigenetic and posttranslational mechanisms

De Bruyne, E., Bos, T. J., Schuit, F., Van Valckenborgh, E., Menu, E., Thorrez, L., Atadja, P., Jernberg-Wiklund, H., & Vanderkerken, K. (2010) · Blood

Multiple Myeloma Research and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 103

Detecting S-adenosyl-l-methionine-induced conformational change of a histone methyltransferase using a homogeneous time-resolved fluorescence-based binding assay

Lin, Y., Fan, H., Frederiksen, M., Zhao, K., Jiang, L., Wang, Z., Zhou, S., Guo, W., Gao, J., Li, S., et al. (2012) · Analytical Biochemistry

Cancer-related gene regulationEpigenetics and DNA Methylation

Cited by 15