Manfredi, James J.

The Mdm2–p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

Manfredi, J. J. (2010) · Genes & Development

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 344

Multiple roles of the tumor suppressor p53

Bargonetti, J., & Manfredi, J. J. (2002) · Current Opinion in Oncology

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 332

E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repression

Carvajal, L. A., Hamard, P.-J., Tonnessen, C., & Manfredi, J. J. (2012) · Genes & Development

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 151

Another fork in the road—life or death decisions by the tumour suppressor p53

Carvajal, L. A., & Manfredi, J. J. (2013) · The EMBO Reports

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 149

A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes

Thornborrow, E. C., Patel, S., Mastropietro, A. E., Schwartzfarb, E. M., & Manfredi, J. J. (2002) · Oncogene

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 132

USP7 enforces heterochromatinization of p53 target promoters by protecting SUV39H1 from MDM2-mediated degradation.

Mungamuri, S. K., Qiao, R. F., Yao, S., Manfredi, J. J., Gu, W., & Aaronson, S. A. (2016) · Cell Reports

Ubiquitin and proteasome pathwaysCancer-related Molecular Pathways

Cited by 54