Littlefield, Peter

Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

Pruneda, J. N., Littlefield, P. J., Soss, S. E., Nordquist, K. A., Chazin, W. J., Brzovic, P. S., & Klevit, R. E. (2012) · Molecular Cell

Ubiquitin and proteasome pathwaysEnzyme Structure and Function

Cited by 333

The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex

Brzovic, P. S., Heikaus, C. C., Kisselev, L., Vernon, R., Herbig, E., Pacheco, D., Warfield, L., Littlefield, P., Baker, D., Klevit, R. E., et al. (2011) · Molecular Cell

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 203

Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations

Littlefield, P., Liu, L., Mysore, V., Shan, Y., Shaw, D. E., & Jura, N. (2014) · Science Signaling

HER2/EGFR in Cancer ResearchLung Cancer Treatments and Mutations

Cited by 126