Sharp, Zelton Dave

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Harrison, D. E., Strong, R., Sharp, Z. D., Nelson, J. F., Astle, C. M., Flurkey, K., Nadon, N. L., Wilkinson, J. E., Frenkel, K., Carter, C. S., et al. (2009) · Nature

Genetics, Aging, and Longevity in Model OrganismsPI3K/AKT/mTOR signaling in cancer

Cited by 3,766

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

Miller, R. A., Harrison, D. E., Astle, C. M., Baur, J. A., Boyd, A. R., de Cabo, R., Fernandez, E., Flurkey, K., Javors, M. A., Nelson, J. F., et al. (2011) · The Journals of Gerontology: Series A

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 896

Association of BRCA1 with the hRad50-hMre11-p95 Complex and the DNA Damage Response

Zhong, Q., Chen, C.-F., Li, S., Chen, Y., Wang, C.-C., Xiao, J., Chen, P.-L., Sharp, Z. D., & Lee, W.-H. (1999) · Science

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 626

Expression of BRC Repeats in Breast Cancer Cells Disrupts the BRCA2-Rad51 Complex and Leads to Radiation Hypersensitivity and Loss of G2/M Checkpoint Control

Chen, C.-F., Chen, P.-L., Zhong, Q., Sharp, Z. D., & Lee, W.-H. (1999) · Journal of Biological Chemistry

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 207

Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs

Calhoun, C., Shivshankar, P., Saker, M., Sloane, L. B., Livi, C. B., Sharp, Z. D., Orihuela, C. J., Adnot, S., White, E. S., Richardson, A., et al. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 92