Schroder, Kate

The Inflammasomes

Schroder, K., & Tschopp, J. (2010) · Cell

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 5,475

Interferon-γ: an overview of signals, mechanisms and functions

Schroder, K., Hertzog, P. J., Ravasi, T., & Hume, D. A. (2004) · Journal of Leukocyte Biology

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 4,120

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Coll, R. C., Robertson, A. A. B., Chae, J. J., Higgins, S. C., Muñoz-Planillo, R., Inserra, M. C., Vetter, I., Dungan, L. S., Monks, B. G., Stutz, A., et al. (2015) · Nature Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,849

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

Mridha, A. R., Wree, A., Robertson, A. A. B., Yeh, M. M., Johnson, C. D., Van Rooyen, D. M., Haczeyni, F., Teoh, N. C.-H., Savard, C., Ioannou, G. N., et al. (2017) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentInflammasome and immune disorders

Cited by 1,110

Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice

Gordon, R., Albornoz, E. A., Christie, D. C., Langley, M. R., Kumar, V., Mantovani, S., Robertson, A. A. B., Butler, M. S., Rowe, D. B., O’Neill, L. A., et al. (2018) · Science Translational Medicine

Parkinson's Disease Mechanisms and TreatmentsInflammasome and immune disorders

Cited by 897

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

Conos, S. A., Chen, K. W., De Nardo, D., Hara, H., Whitehead, L., Núñez, G., Masters, S. L., Murphy, J. M., Schroder, K., Vaux, D. L., et al. (2017) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 485

Signal integration between IFNγ and TLR signalling pathways in macrophages

Schroder, K., Sweet, M. J., & Hume, D. A. (2006) · Immunobiology

Immune Response and InflammationImmune responses and vaccinations

Cited by 288

The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins

Deora, V., Lee, J. D., Albornoz, E. A., McAlary, L., Jagaraj, C. J., Robertson, A. A. B., Atkin, J. D., Cooper, M. A., Schroder, K., Yerbury, J. J., et al. (2020) · Glia

Inflammasome and immune disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 245

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

Halili, M. A., Andrews, M. R., Labzin, L. I., Schroder, K., Matthias, G., Cao, C., Lovelace, E., Reid, R. C., Le, G. T., Hume, D. A., et al. (2010) · Journal of Leukocyte Biology

Histone Deacetylase Inhibitors ResearchImmune Response and Inflammation

Cited by 186

Salmonella employs multiple mechanisms to subvert the TLR‐inducible zinc‐mediated antimicrobial response of human macrophages

Kapetanovic, R., Bokil, N. J., Achard, M. E. S., Ong, C. Y., Peters, K. M., Stocks, C. J., Phan, M., Monteleone, M., Schroder, K., Irvine, K. M., et al. (2016) · The FASEB Journal

Immune Response and InflammationSalmonella and Campylobacter epidemiology

Cited by 86

The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells

Kubosaki, A., Lindgren, G., Tagami, M., Simon, C., Tomaru, Y., Miura, H., Suzuki, T., Arner, E., Forrest, A. R. R., Irvine, K. M., et al. (2010) · Molecular Immunology

interferon and immune responsesGenomics and Chromatin Dynamics

Cited by 29