Tough, David F.

Turnover of naive- and memory-phenotype T cells.

Tough, D. F., & Sprent, J. (1994) · The Journal of experimental medicine

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 869

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription

Kaikkonen, M. U., Spann, N. J., Heinz, S., Romanoski, C. E., Allison, K. A., Stender, J. D., Chun, H. B., Tough, D. F., Prinjha, R. K., Benner, C., et al. (2013) · Molecular Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 672

In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection

Zhang, Y., Wallace, D. L., De Lara, C. M., Ghattas, H., Asquith, B., Worth, A., Griffin, G. E., Taylor, G. P., Tough, D. F., Beverley, P. C. L., et al. (2007) · Immunology

Immune Cell Function and InteractionT-cell and B-cell Immunology

Cited by 376

Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

Cano-Gamez, K., Soskic, B., Roumeliotis, T. I., So, E., Smyth, D. J., Baldrighi, M., Willé, D., Nakic, N., Esparza-Gordillo, J., Larminie, C. G. C., et al. (2020) · Nature Communications

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 274

Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach

Bassi, Z. I., Fillmore, M. C., Miah, A. H., Chapman, T. D., Maller, C., Roberts, E. J., Davis, L. C., Lewis, D. E., Galwey, N. W., Waddington, K. E., et al. (2018) · ACS Chemical Biology

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 186

Direct measurement of T cell subset kinetics in vivo in elderly men and women

Wallace, D. L., Zhang, Y., Ghattas, H., Worth, A., Irvine, A., Bennett, A. R., Griffin, G. E., Beverley, P. C. L., Tough, D. F., & Macallan, D. C. (2004) · The Journal of Immunology

T-cell and B-cell ImmunologyHIV Research and Treatment

Cited by 115

Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives

Ghiboub, M., Elfiky, A. M. I., de Winther, M. P. J., Harker, N. R., Tough, D. F., & de Jonge, W. J. (2021) · Journal of Personalized Medicine

Histone Deacetylase Inhibitors ResearchProtein Degradation and Inhibitors

Cited by 28