Humbert, Sandrine

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

Gauthier, L. R., Charrin, B. C., Borrell-Pagès, M., Dompierre, J. P., Rangone, H., Cordelières, F. P., De Mey, J., MacDonald, M. E., Leßmann, V., Humbert, S., et al. (2004) · Cell

Genetic Neurodegenerative DiseasesHereditary Neurological Disorders

Cited by 1,178

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

Dompierre, J. P., Godin, J. D., Charrin, B. C., Cordelières, F. P., King, S. J., Humbert, S., & Saudou, F. (2007) · The Journal of Neuroscience

Genetic Neurodegenerative DiseasesHistone Deacetylase Inhibitors Research

Cited by 792

Huntington’s disease alters human neurodevelopment

Barnat, M., Capizzi, M., Aparicio, E., Boluda, S., Wennagel, D., Kacher, R., Kassem, R., Lenoir, S., Agasse, F., Braz, B. Y., et al. (2020) · Science

Genetic Neurodegenerative DiseasesNeurogenesis and neuroplasticity mechanisms

Cited by 326

Potential function for the Huntingtin protein as a scaffold for selective autophagy

Ochaba, J., Lukacsovich, T., Csikos, G., Zheng, S., Margulis, J., Salazar, L., Mao, K., Lau, A. L., Yeung, S. Y., Humbert, S., et al. (2014) · Proceedings of the National Academy of Sciences

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 308

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

Aillaud, C., Bosc, C., Peris, L., Bosson, A., Heemeryck, P., Van Dijk, J., Le Friec, J., Boulan, B., Vossier, F., Sanman, L. E., et al. (2017) · Science

Microtubule and mitosis dynamicsNeurogenesis and neuroplasticity mechanisms

Cited by 293

The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin

Rangone, H., Poizat, G., Troncoso, J., Ross, C. A., MacDonald, M. E., Saudou, F., & Humbert, S. (2004) · European Journal of Neuroscience

Genetic Neurodegenerative DiseasesGenetics and Neurodevelopmental Disorders

Cited by 144

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

Galvan, L., Francelle, L., Gaillard, M.-C., de Longprez, L., Carrillo-de Sauvage, M.-A., Liot, G., Cambon, K., Stimmer, L., Luccantoni, S., Flament, J., et al. (2018) · Brain

Genetic Neurodegenerative DiseasesGenetics and Neurodevelopmental Disorders

Cited by 47

Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin

Agasse, F., Mendez-David, I., Christaller, W., Carpentier, R., Braz, B. Y., David, D. J., Saudou, F., & Humbert, S. (2020) · Cell Reports

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 43