Karns, Rebekah

FXR is a molecular target for the effects of vertical sleeve gastrectomy

Ryan, K. K., Tremaroli, V., Clemmensen, C., Kovatcheva-Datchary, P., Myronovych, A., Karns, R., Wilson-Pérez, H. E., Sandoval, D. A., Kohli, R., Bäckhed, F., et al. (2014) · Nature

Bariatric Surgery and OutcomesGut microbiota and health

Cited by 931

Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids

Ouchi, R., Togo, S., Kimura, M., Shinozawa, T., Koido, M., Koike, H., Thompson, W., Karns, R. A., Mayhew, C. N., McGrath, P. S., et al. (2019) · Cell Metabolism

Pluripotent Stem Cells ResearchLiver Disease Diagnosis and Treatment

Cited by 537

De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation

Schaub, J. R., Huppert, K. A., Kurial, S. N. T., Hsu, B. Y., Cast, A. E., Donnelly, B., Karns, R. A., Chen, F., Rezvani, M., Luu, H. Y., et al. (2018) · Nature

Liver physiology and pathologyPediatric Hepatobiliary Diseases and Treatments

Cited by 289

Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells

Nalapareddy, K., Nattamai, K. J., Kumar, R. S., Karns, R., Wikenheiser-Brokamp, K. A., Sampson, L. L., Mahe, M. M., Sundaram, N., Yacyshyn, M.-B., Yacyshyn, B., et al. (2017) · Cell Reports

Wnt/β-catenin signaling in development and cancerGenetics, Aging, and Longevity in Model Organisms

Cited by 280

High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery

Xanthakos, S. A., Jenkins, T. M., Kleiner, D. E., Boyce, T. W., Mourya, R., Karns, R., Brandt, M. L., Harmon, C. M., Helmrath, M. A., Michalsky, M. P., et al. (2015) · Gastroenterology

Liver Disease Diagnosis and TreatmentBariatric Surgery and Outcomes

Cited by 151

Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice

Miethke, A. G., Zhang, W., Simmons, J., Taylor, A. E., Shi, T., Shanmukhappa, S. K., Karns, R., White, S., Jegga, A. G., Lages, C. S., et al. (2016) · Hepatology

Drug Transport and Resistance MechanismsLiver Diseases and Immunity

Cited by 141

Haematopoietic stem cells in perisinusoidal niches are protected from ageing

Saçma, M., Pospiech, J., Bogeska, R., de Back, W., Mallm, J.-P., Sakk, V., Soller, K., Marka, G., Vollmer, A., Karns, R., et al. (2019) · Nature Cell Biology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 133

Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease

Moreno-Fernandez, M. E., Giles, D. A., Stankiewicz, T. E., Sheridan, R., Karns, R., Cappelletti, M., Lampe, K., Mukherjee, R., Sina, C., Sallese, A., et al. (2018) · JCI Insight

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 106