Popel, Aleksander S.

Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis

Lee, E., Fertig, E. J., Jin, K., Sukumar, S., Pandey, N. B., & Popel, A. S. (2014) · Nature Communications

Lymphatic System and DiseasesCancer Cells and Metastasis

Cited by 197

Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence

Zhang, S., Yuan, L., Danilova, L., Mo, G., Zhu, Q., Deshpande, A., Bell, A. T. F., Elisseeff, J., Popel, A. S., Anders, R. A., et al. (2023) · Genome Medicine

Hepatocellular Carcinoma Treatment and PrognosisCancer Immunotherapy and Biomarkers

Cited by 140

From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling

Wang, H., Arulraj, T., Ippolito, A., & Popel, A. S. (2024) · npj Digital Medicine

Statistical Methods in Clinical TrialsMathematical Biology Tumor Growth

Cited by 122

Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells

Chen, K., & Popel, A. S. (2006) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 82

Multiscale Modeling in the Clinic: Drug Design and Development

Clancy, C. E., An, G., Cannon, W. R., Liu, Y., May, E. E., Ortoleva, P., Popel, A. S., Sluka, J. P., Su, J., Vicini, P., et al. (2016) · Annals of Biomedical Engineering

Computational Drug Discovery MethodsStatistical Methods in Clinical Trials

Cited by 62

Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth

Furukawa, N., Yang, W., Chao, A., Patil, A., Mirando, A., Pandey, N., & Popel, A. (2023) · Cell Death Discovery

Cell death mechanisms and regulationAntimicrobial Peptides and Activities

Cited by 10

Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth

Furukawa, N., Yang, W., Chao, A. R., Patil, A., Mirando, A. C., Pandey, N. B., & Popel, A. S. (2024) · Cell Death Discovery

Cell death mechanisms and regulationAntimicrobial Peptides and Activities

Cited by 10

Quantitative Systems Pharmacology Modeling in Immuno-Oncology: Hypothesis Testing, Dose Optimization, and Efficacy Prediction

Wang, H., Arulraj, T., Ippolito, A., & Popel, A. S. (2024) · Handbook of Experimental Pharmacology

Mathematical Biology Tumor GrowthCancer Immunotherapy and Biomarkers

Cited by 6

Structured Schemas for Provenance-Rich, LLM-Assisted QSP Model Calibration

Eliason, J., & Popel, A. S. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Biomedical Text Mining and OntologiesComputational Drug Discovery Methods

Cited by 0

Structured Schemas for Provenance‐Rich, LLM ‐Assisted QSP Model Calibration

Eliason, J., & Popel, A. S. (2026) · CPT: Pharmacometrics & Systems Pharmacology

Biomedical Text Mining and OntologiesComputational Drug Discovery Methods

Cited by 0